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Guardant Health

364 hedge funds and large institutions have $6.47B invested in Guardant Health in 2025 Q2 according to their latest regulatory filings, with 69 funds opening new positions, 128 increasing their positions, 115 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

57% more first-time investments, than exits

New positions opened: 69 | Existing positions closed: 44

27% more capital invested

Capital invested by funds: $5.1B → $6.47B (+$1.37B)

11% more repeat investments, than reductions

Existing positions increased: 128 | Existing positions reduced: 115

7% more funds holding

Funds holding: 341364 (+23)

3.34% more ownership

Funds ownership: 97%100.34% (+3.3%)

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

30% less call options, than puts

Call options by funds: $89.1M | Put options by funds: $126M

Holders
364
Holders Change
+23
Holders Change %
+6.74%
% of All Funds
4.79%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
69
Increased
128
Reduced
115
Closed
44
Calls
$89.1M
Puts
$126M
Net Calls
-$37.3M
Net Calls Change
-$4.9M
Name Holding Trade Value Shares
Change
Change in
Stake
NIM
201
NEOS Investment Management
Connecticut
$591K +$53.1K +1,190 +12%
TE
202
Tema ETFs
New York
$591K +$53.1K +1,190 +12%
ET
203
Entropy Technologies
New York
$579K +$272K +6,087 +121%
GAM
204
Groupama Asset Management
France
$576K
SOW
205
State of Wyoming
Wyoming
$567K +$486K +10,890 New
BM
206
Brandywine Managers
Delaware
$533K
ITFISA
207
Investors Towarzystwo Funduszy Inwestycyjnych Spolka Akcyjna
$531K +$188K +4,200 +70%
Polen Capital Management
208
Polen Capital Management
Florida
$530K +$455K +10,183 New
Commonwealth Equity Services
209
Commonwealth Equity Services
Massachusetts
$497K -$37.6K -841 -8%
Truist Financial
210
Truist Financial
North Carolina
$495K -$26.4K -591 -6%
X
211
Xponance
Pennsylvania
$486K +$10.2K +228 +3%
OQS
212
Occudo Quantitative Strategies
Florida
$476K +$409K +9,148 New
IC
213
IEQ Capital
California
$472K -$287K -6,417 -41%
CH
214
Canton Hathaway
Rhode Island
$462K +$26.4K +590 +7%
CII
215
Capital International Inc
California
$460K -$135K -3,022 -25%
GCP
216
GSA Capital Partners
United Kingdom
$448K +$384K +8,604 New
BCV
217
Banque Cantonale Vaudoise
Switzerland
$434K -$11.1K -248 -3%
VPIM
218
Vanguard Personalized Indexing Management
California
$430K +$57.2K +1,280 +18%
WAP
219
Wealthcare Advisory Partners
Pennsylvania
$428K +$313 +7 +0.1%
Bank of Montreal
220
Bank of Montreal
Ontario, Canada
$427K +$3.93K +88 +1%
FCM
221
Farallon Capital Management
California
$416K +$357K +8,000 New
Jones Financial Companies
222
Jones Financial Companies
Missouri
$414K +$149K +3,341 +70%
RAM
223
RWC Asset Management
United Kingdom
$407K +$349K +7,819 New
FA
224
Fiduciary Alliance
South Carolina
$404K -$112K -2,515 -24%
Mackenzie Financial
225
Mackenzie Financial
Ontario, Canada
$398K +$5.09K +114 +2%

GH Hedge Fund Activity: Q2 2025 in Review

364 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q2 2025, worth a combined $6.47B — up 27% from $5.1B a quarter earlier.

Buyers outnumbered sellers: 69 funds opened new GH positions and 44 closed out — a net gain of 25 holders — while 128 added to existing stakes and 115 trimmed.

The largest buyer was Millennium Management, adding an estimated $72.6M. The largest seller was Cadian Capital Management, cutting an estimated $63.2M.

  • 364 institutional investors held Guardant Health (GH) as of Q2 2025, up from 341 in Q1 2025.
  • Funds reported $6.47B of Guardant Health stock for Q2 2025, up 27% quarter-over-quarter.
  • 69 funds opened new Guardant Health positions in Q2 2025 and 44 closed out, a net change of +25 holders.
  • The largest Guardant Health buyer in Q2 2025 was Millennium Management, an estimated $72.6M added.
  • The largest Guardant Health seller in Q2 2025 was Cadian Capital Management, an estimated $63.2M sold.

Based on aggregated 13F filings for Q2 2025.