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Guardant Health

364 hedge funds and large institutions have $6.47B invested in Guardant Health in 2025 Q2 according to their latest regulatory filings, with 69 funds opening new positions, 128 increasing their positions, 115 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

57% more first-time investments, than exits

New positions opened: 69 | Existing positions closed: 44

27% more capital invested

Capital invested by funds: $5.1B → $6.47B (+$1.37B)

11% more repeat investments, than reductions

Existing positions increased: 128 | Existing positions reduced: 115

7% more funds holding

Funds holding: 341364 (+23)

3.34% more ownership

Funds ownership: 97%100.34% (+3.3%)

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

30% less call options, than puts

Call options by funds: $89.1M | Put options by funds: $126M

Holders
364
Holders Change
+23
Holders Change %
+6.74%
% of All Funds
4.79%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
69
Increased
128
Reduced
115
Closed
44
Calls
$89.1M
Puts
$126M
Net Calls
-$37.3M
Net Calls Change
-$4.9M
Name Holding Trade Value Shares
Change
Change in
Stake
CL
176
CSS LLC
Illinois
$1.17M
OCM
177
One Capital Management
California
$1.15M +$986K +22,084 New
CWM
178
CIBC World Markets
New York
$1.14M -$542K -12,138 -45%
FFL
179
Future Fund LLC
Illinois
$1.13M +$971K +21,730 New
MMEA
180
Main Management ETF Advisors
California
$1.11M +$15.5K +348 +2%
Janney Montgomery Scott
181
Janney Montgomery Scott
Pennsylvania
$1.07M +$676K +15,128 +278%
SO
182
STRS Ohio
Ohio
$1.06M +$62.5K +1,400 +7%
Jacobs Levy Equity Management
183
Jacobs Levy Equity Management
New Jersey
$978K +$839K +18,790 New
Teacher Retirement System of Texas
184
Teacher Retirement System of Texas
Texas
$954K -$89K -1,992 -10%
QIM
185
Quantitative Investment Management
Virginia
$923K +$793K +17,749 New
ETC
186
Exchange Traded Concepts
Oklahoma
$914K -$247K -5,536 -24%
GCM
187
Graham Capital Management
Connecticut
$884K +$464K +10,382 +157%
BF
188
BOK Financial
Oklahoma
$880K -$30.6K -685 -4%
MAG
189
MRA Advisory Group
New Jersey
$851K +$48.1K +1,078 +7%
MP
190
Mangrove Partners
Connecticut
$815K
Capstone Investment Advisors
191
Capstone Investment Advisors
New York
$788K +$676K +15,142 New
TRCT
192
Tower Research Capital (TRC)
New York
$785K +$499K +11,163 +284%
BCM
193
Bayesian Capital Management
New York
$762K +$654K +14,652 New
ORI
194
Oak Ridge Investments
Illinois
$738K -$33.2K -743 -5%
MCA
195
MSH Capital Advisors
Arizona
$669K -$101K -2,270 -15%
Rockefeller Capital Management
196
Rockefeller Capital Management
New York
$666K +$572K +12,802 New
P8IP
197
Pier 88 Investment Partners
California
$645K +$554K +12,400 New
Cambridge Investment Research Advisors
198
Cambridge Investment Research Advisors
Iowa
$637K -$14.1K -315 -3%
Public Employees Retirement Association of Colorado
199
Public Employees Retirement Association of Colorado
Colorado
$635K -$55.6K -1,245 -9%
AIP
200
Ameritas Investment Partners
Nebraska
$635K +$7.24K +162 +1%

GH Hedge Fund Activity: Q2 2025 in Review

364 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q2 2025, worth a combined $6.47B — up 27% from $5.1B a quarter earlier.

Buyers outnumbered sellers: 69 funds opened new GH positions and 44 closed out — a net gain of 25 holders — while 128 added to existing stakes and 115 trimmed.

The largest buyer was Millennium Management, adding an estimated $72.6M. The largest seller was Cadian Capital Management, cutting an estimated $63.2M.

  • 364 institutional investors held Guardant Health (GH) as of Q2 2025, up from 341 in Q1 2025.
  • Funds reported $6.47B of Guardant Health stock for Q2 2025, up 27% quarter-over-quarter.
  • 69 funds opened new Guardant Health positions in Q2 2025 and 44 closed out, a net change of +25 holders.
  • The largest Guardant Health buyer in Q2 2025 was Millennium Management, an estimated $72.6M added.
  • The largest Guardant Health seller in Q2 2025 was Cadian Capital Management, an estimated $63.2M sold.

Based on aggregated 13F filings for Q2 2025.