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Guardant Health

394 hedge funds and large institutions have $7.65B invested in Guardant Health in 2025 Q3 according to their latest regulatory filings, with 71 funds opening new positions, 134 increasing their positions, 132 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

82% more first-time investments, than exits

New positions opened: 71 | Existing positions closed: 39

50% more funds holding in top 10

Funds holding in top 10: 69 (+3)

18% more capital invested

Capital invested by funds: $6.47B → $7.65B (+$1.19B)

8% more funds holding

Funds holding: 364394 (+30)

2% more repeat investments, than reductions

Existing positions increased: 134 | Existing positions reduced: 132

10% less call options, than puts

Call options by funds: $156M | Put options by funds: $173M

2.09% less ownership

Funds ownership: 100.34%98.24% (-2.1%)

Holders
394
Holders Change
+30
Holders Change %
+8.24%
% of All Funds
5.17%
Holding in Top 10
9
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+50%
% of All Funds
0.12%
New
71
Increased
134
Reduced
132
Closed
39
Calls
$156M
Puts
$173M
Net Calls
-$16.8M
Net Calls Change
+$20.6M
Name Holding Trade Value Shares
Change
Change in
Stake
JFG
126
Jefferies Financial Group
New York
$4.37M +$3.69M +67,796 +3,224%
Walleye Capital
127
Walleye Capital
New York
$4.3M +$3.65M +67,175 +4,152%
HF
128
HRT Financial
New York
$4.27M +$3.72M +68,347 New
Dimensional Fund Advisors
129
Dimensional Fund Advisors
Texas
$4.06M +$1.81M +33,241 +105%
HS
130
HighVista Strategies
Massachusetts
$4.04M +$1.98M +36,318 +128%
Janus Henderson Group
131
Janus Henderson Group
United Kingdom
$4.03M -$399K -7,334 -10%
GC
132
Guggenheim Capital
Illinois
$4.01M -$1.25M -23,056 -26%
ACM
133
Adalta Capital Management
New York
$3.95M -$4.08K -75 -0.1%
Creative Planning
134
Creative Planning
Kansas
$3.85M +$353K +6,493 +12%
N
135
Natixis
France
$3.62M +$3.15M +57,900 New
BNP Paribas Financial Markets
136
BNP Paribas Financial Markets
France
$3.61M -$4.42M -81,183 -58%
JRP
137
Jasper Ridge Partners
California
$3.32M
IIM
138
INTECH Investment Management
Florida
$3.19M -$623K -11,458 -18%
Pathstone Holdings
139
Pathstone Holdings
New Jersey
$3.16M +$1.41M +25,922 +105%
Lazard Asset Management
140
Lazard Asset Management
New York
$3.16M +$1.13M +20,855 +70%
PP
141
PDT Partners
New York
$3.15M -$2.83M -52,034 -51%
RPAM
142
Rhenman & Partners Asset Management
Sweden
$3.12M +$2.72M +50,000 New
FMI
143
F/M Investments
District of Columbia
$2.95M +$441K +8,105 +21%
JF
144
Jump Financial
Illinois
$2.81M -$2.72M -50,011 -53%
Stifel Financial
145
Stifel Financial
Missouri
$2.81M -$108K -1,977 -4%
Calamos Advisors
146
Calamos Advisors
Illinois
$2.78M +$2.42M +44,500 New
DekaBank Deutsche Girozentrale
147
DekaBank Deutsche Girozentrale
Germany
$2.78M
Envestnet Asset Management
148
Envestnet Asset Management
Illinois
$2.61M +$169K +3,109 +8%
FFL
149
Future Fund LLC
Illinois
$2.58M +$1.06M +19,556 +90%
State of New Jersey Common Pension Fund D
150
State of New Jersey Common Pension Fund D
New Jersey
$2.55M -$546K -10,036 -20%

GH Hedge Fund Activity: Q3 2025 in Review

394 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q3 2025, worth a combined $7.65B — up 18% from $6.47B a quarter earlier.

Buyers outnumbered sellers: 71 funds opened new GH positions and 39 closed out — a net gain of 32 holders — while 134 added to existing stakes and 132 trimmed.

The largest buyer was T. Rowe Price Associates, adding an estimated $134M. The largest seller was Citadel Advisors, cutting an estimated $143M.

  • 394 institutional investors held Guardant Health (GH) as of Q3 2025, up from 364 in Q2 2025.
  • Funds reported $7.65B of Guardant Health stock for Q3 2025, up 18% quarter-over-quarter.
  • 71 funds opened new Guardant Health positions in Q3 2025 and 39 closed out, a net change of +32 holders.
  • The largest Guardant Health buyer in Q3 2025 was T. Rowe Price Associates, an estimated $134M added.
  • The largest Guardant Health seller in Q3 2025 was Citadel Advisors, an estimated $143M sold.

Based on aggregated 13F filings for Q3 2025.