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Guardant Health

364 hedge funds and large institutions have $6.47B invested in Guardant Health in 2025 Q2 according to their latest regulatory filings, with 69 funds opening new positions, 128 increasing their positions, 115 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

57% more first-time investments, than exits

New positions opened: 69 | Existing positions closed: 44

27% more capital invested

Capital invested by funds: $5.1B → $6.47B (+$1.37B)

11% more repeat investments, than reductions

Existing positions increased: 128 | Existing positions reduced: 115

7% more funds holding

Funds holding: 341364 (+23)

3.34% more ownership

Funds ownership: 97%100.34% (+3.3%)

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

30% less call options, than puts

Call options by funds: $89.1M | Put options by funds: $126M

Holders
364
Holders Change
+23
Holders Change %
+6.74%
% of All Funds
4.79%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
69
Increased
128
Reduced
115
Closed
44
Calls
$89.1M
Puts
$126M
Net Calls
-$37.3M
Net Calls Change
-$4.9M
Name Holding Trade Value Shares
Change
Change in
Stake
CM
101
Castleark Management
Illinois
$6.33M +$5.43M +121,560 New
Wells Fargo
102
Wells Fargo
California
$6.24M -$2.55M -57,052 -32%
State of Wisconsin Investment Board
103
State of Wisconsin Investment Board
Wisconsin
$6.08M -$606K -13,569 -10%
Mirae Asset Global ETFs Holdings
104
Mirae Asset Global ETFs Holdings
Hong Kong
$5.8M +$1.8M +40,209 +56%
California State Teachers Retirement System (CalSTRS)
105
California State Teachers Retirement System (CalSTRS)
California
$5.51M -$596K -13,334 -11%
New York State Common Retirement Fund
106
New York State Common Retirement Fund
New York
$5.46M -$90.6K -2,029 -2%
Russell Investments Group
107
Russell Investments Group
United Kingdom
$5.43M +$1.38M +30,802 +42%
PP
108
PDT Partners
New York
$5.33M -$4.7M -105,339 -51%
RAM
109
Readystate Asset Management
Illinois
$5.21M +$4.47M +100,085 New
CC
110
Casdin Capital
New York
$5.2M -$6.7M -150,000 -60%
EAM
111
Exome Asset Management
New York
$5.11M -$1.3M -29,000 -23%
American Century Companies
112
American Century Companies
Missouri
$5M -$364K -8,152 -8%
JF
113
Jump Financial
Illinois
$4.94M +$4.24M +95,011 New
SP
114
SWS Partners
Ohio
$4.84M -$524K -11,740 -11%
ACM
115
Atika Capital Management
New York
$4.64M +$165K +3,700 +4%
SFI
116
Susquehanna Fundamental Investments
Pennsylvania
$4.6M
GC
117
Guggenheim Capital
Illinois
$4.54M +$94.3K +2,111 +2%
Neuberger Berman Group
118
Neuberger Berman Group
New York
$4.46M -$2.09M -46,835 -35%
Citigroup
119
Citigroup
New York
$4.35M -$544K -12,190 -13%
AQR Capital Management
120
AQR Capital Management
Connecticut
$4.17M +$384K +8,597 +12%
SEI Investments
121
SEI Investments
Pennsylvania
$4.02M -$194K -4,347 -5%
LCM
122
Landscape Capital Management
New Jersey
$3.94M +$1.96M +43,961 +139%
DFCM
123
Dark Forest Capital Management
Puerto Rico
$3.85M +$2.13M +47,758 +182%
PC
124
Pier Capital
Connecticut
$3.77M -$2.26M -50,555 -41%
Janus Henderson Group
125
Janus Henderson Group
United Kingdom
$3.74M +$679K +15,207 +27%

GH Hedge Fund Activity: Q2 2025 in Review

364 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q2 2025, worth a combined $6.47B — up 27% from $5.1B a quarter earlier.

Buyers outnumbered sellers: 69 funds opened new GH positions and 44 closed out — a net gain of 25 holders — while 128 added to existing stakes and 115 trimmed.

The largest buyer was Millennium Management, adding an estimated $72.6M. The largest seller was Cadian Capital Management, cutting an estimated $63.2M.

  • 364 institutional investors held Guardant Health (GH) as of Q2 2025, up from 341 in Q1 2025.
  • Funds reported $6.47B of Guardant Health stock for Q2 2025, up 27% quarter-over-quarter.
  • 69 funds opened new Guardant Health positions in Q2 2025 and 44 closed out, a net change of +25 holders.
  • The largest Guardant Health buyer in Q2 2025 was Millennium Management, an estimated $72.6M added.
  • The largest Guardant Health seller in Q2 2025 was Cadian Capital Management, an estimated $63.2M sold.

Based on aggregated 13F filings for Q2 2025.