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Guardant Health

394 hedge funds and large institutions have $7.65B invested in Guardant Health in 2025 Q3 according to their latest regulatory filings, with 71 funds opening new positions, 134 increasing their positions, 132 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

82% more first-time investments, than exits

New positions opened: 71 | Existing positions closed: 39

50% more funds holding in top 10

Funds holding in top 10: 69 (+3)

18% more capital invested

Capital invested by funds: $6.47B → $7.65B (+$1.19B)

8% more funds holding

Funds holding: 364394 (+30)

2% more repeat investments, than reductions

Existing positions increased: 134 | Existing positions reduced: 132

10% less call options, than puts

Call options by funds: $156M | Put options by funds: $173M

2.09% less ownership

Funds ownership: 100.34%98.24% (-2.1%)

Holders
394
Holders Change
+30
Holders Change %
+8.24%
% of All Funds
5.17%
Holding in Top 10
9
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+50%
% of All Funds
0.12%
New
71
Increased
134
Reduced
132
Closed
39
Calls
$156M
Puts
$173M
Net Calls
-$16.8M
Net Calls Change
+$20.6M
Name Holding Trade Value Shares
Change
Change in
Stake
California Public Employees Retirement System
76
California Public Employees Retirement System
California
$12.9M +$3M +55,123 +36%
SEI Investments
77
SEI Investments
Pennsylvania
$12.6M +$6.75M +124,019 +160%
RG
78
Rathbones Group
United Kingdom
$12.5M -$320K -5,877 -3%
Russell Investments Group
79
Russell Investments Group
United Kingdom
$12.2M +$4.95M +90,931 +87%
TD Asset Management
80
TD Asset Management
Ontario, Canada
$11.8M +$1.43M +26,210 +16%
First Trust Advisors
81
First Trust Advisors
Illinois
$11.6M -$873K -16,052 -8%
GIP
82
Granite Investment Partners
California
$11.6M -$11M -201,565 -52%
ACM
83
Aquatic Capital Management
Illinois
$11.5M +$1.5M +27,612 +18%
RhumbLine Advisers
84
RhumbLine Advisers
Massachusetts
$11.3M -$248K -4,557 -2%
Mitsubishi UFJ Trust & Banking
85
Mitsubishi UFJ Trust & Banking
Japan
$11.1M -$279K -5,134 -3%
Canada Pension Plan Investment Board
86
Canada Pension Plan Investment Board
Ontario, Canada
$11.1M +$9.23M +169,700 +2,233%
Principal Financial Group
87
Principal Financial Group
Iowa
$11M -$4.68M -86,006 -33%
CS
88
Candriam SCA
Luxembourg
$10.7M +$67K +1,231 +0.7%
CM
89
Castleark Management
Illinois
$10M +$2.1M +38,513 +32%
Allianz Asset Management
90
Allianz Asset Management
Germany
$9.92M -$30.8K -567 -0.4%
HIM
91
Hillsdale Investment Management
Ontario, Canada
$9.74M +$1.08M +19,800 +15%
Adage Capital Partners
92
Adage Capital Partners
Massachusetts
$9.5M -$8.44M -155,183 -50%
Legal & General Group
93
Legal & General Group
United Kingdom
$9.47M -$352K -6,464 -4%
TRSOTSOK
94
Teachers Retirement System of the State of Kentucky
Kentucky
$9.44M +$152K +2,800 +2%
Connor, Clark & Lunn Investment Management (CC&L)
95
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$9.08M +$7.91M +145,360 New
AllianceBernstein
96
AllianceBernstein
Tennessee
$8.72M -$42.7K -785 -0.6%
ACM
97
Atika Capital Management
New York
$8.31M +$2.38M +43,800 +49%
Cerity Partners
98
Cerity Partners
New York
$8.18M -$729K -13,404 -9%
Neuberger Berman Group
99
Neuberger Berman Group
New York
$8.02M +$2.32M +42,701 +50%
CCM
100
Cinctive Capital Management
New York
$7.57M +$6.59M +121,130 New

GH Hedge Fund Activity: Q3 2025 in Review

394 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q3 2025, worth a combined $7.65B — up 18% from $6.47B a quarter earlier.

Buyers outnumbered sellers: 71 funds opened new GH positions and 39 closed out — a net gain of 32 holders — while 134 added to existing stakes and 132 trimmed.

The largest buyer was T. Rowe Price Associates, adding an estimated $134M. The largest seller was Citadel Advisors, cutting an estimated $143M.

  • 394 institutional investors held Guardant Health (GH) as of Q3 2025, up from 364 in Q2 2025.
  • Funds reported $7.65B of Guardant Health stock for Q3 2025, up 18% quarter-over-quarter.
  • 71 funds opened new Guardant Health positions in Q3 2025 and 39 closed out, a net change of +32 holders.
  • The largest Guardant Health buyer in Q3 2025 was T. Rowe Price Associates, an estimated $134M added.
  • The largest Guardant Health seller in Q3 2025 was Citadel Advisors, an estimated $143M sold.

Based on aggregated 13F filings for Q3 2025.