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Guardant Health

364 hedge funds and large institutions have $6.47B invested in Guardant Health in 2025 Q2 according to their latest regulatory filings, with 69 funds opening new positions, 128 increasing their positions, 115 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

57% more first-time investments, than exits

New positions opened: 69 | Existing positions closed: 44

27% more capital invested

Capital invested by funds: $5.1B → $6.47B (+$1.37B)

11% more repeat investments, than reductions

Existing positions increased: 128 | Existing positions reduced: 115

7% more funds holding

Funds holding: 341364 (+23)

3.34% more ownership

Funds ownership: 97%100.34% (+3.3%)

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

30% less call options, than puts

Call options by funds: $89.1M | Put options by funds: $126M

Holders
364
Holders Change
+23
Holders Change %
+6.74%
% of All Funds
4.79%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
69
Increased
128
Reduced
115
Closed
44
Calls
$89.1M
Puts
$126M
Net Calls
-$37.3M
Net Calls Change
-$4.9M
Name Holding Trade Value Shares
Change
Change in
Stake
UBS Group
26
UBS Group
Switzerland
$61.6M -$49M -1,097,242 -48%
Northern Trust
27
Northern Trust
Illinois
$61.6M -$4.17M -93,477 -7%
Goldman Sachs
28
Goldman Sachs
New York
$59.7M -$919K -20,577 -2%
Temasek Holdings
29
Temasek Holdings
Singapore
$54.3M
Charles Schwab
30
Charles Schwab
California
$52.7M +$749K +16,766 +2%
Fidelity Investments
31
Fidelity Investments
Massachusetts
$51.4M +$22.2M +497,746 +102%
AAP
32
Aristotle Atlantic Partners
Florida
$48.5M -$1.45M -32,565 -3%
Bank of New York Mellon
33
Bank of New York Mellon
New York
$47.2M +$2.42M +54,173 +6%
Royal Bank of Canada
34
Royal Bank of Canada
Ontario, Canada
$46.5M +$33.3M +744,663 +501%
Lord, Abbett & Co
35
Lord, Abbett & Co
New Jersey
$46.2M -$2.98M -66,777 -7%
Morgan Stanley
36
Morgan Stanley
New York
$46.1M -$2.41M -53,879 -6%
RI
37
RTW Investments
New York
$44.6M +$38.3M +856,501 New
B
38
Braidwell
Connecticut
$43.6M -$21.9M -489,527 -37%
Man Group
39
Man Group
United Kingdom
$41.9M +$33M +739,800 +1,116%
Jennison Associates
40
Jennison Associates
New York
$37.2M +$32M +715,467 New
Bank of America
41
Bank of America
North Carolina
$36.8M +$9.87M +221,039 +45%
EA
42
Emerald Advisers
Pennsylvania
$36.4M +$7.53M +168,498 +32%
Renaissance Technologies
43
Renaissance Technologies
New York
$35.1M +$2.62M +58,700 +10%
EAM
44
Erste Asset Management
Austria
$33.2M
Manulife (Manufacturers Life Insurance)
45
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$32.9M +$2.42M +54,284 +9%
RPI
46
Railway Pension Investments
United Kingdom
$32.3M
PAMP
47
Polar Asset Management Partners
Ontario, Canada
$30.1M +$2.33M +52,144 +10%
Victory Capital Management
48
Victory Capital Management
Texas
$29.5M +$15.5M +346,281 +157%
Balyasny Asset Management
49
Balyasny Asset Management
Illinois
$29.4M -$12.3M -274,644 -33%
VOYA Investment Management
50
VOYA Investment Management
Georgia
$28.6M +$3.42M +76,679 +16%

GH Hedge Fund Activity: Q2 2025 in Review

364 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q2 2025, worth a combined $6.47B — up 27% from $5.1B a quarter earlier.

Buyers outnumbered sellers: 69 funds opened new GH positions and 44 closed out — a net gain of 25 holders — while 128 added to existing stakes and 115 trimmed.

The largest buyer was Millennium Management, adding an estimated $72.6M. The largest seller was Cadian Capital Management, cutting an estimated $63.2M.

  • 364 institutional investors held Guardant Health (GH) as of Q2 2025, up from 341 in Q1 2025.
  • Funds reported $6.47B of Guardant Health stock for Q2 2025, up 27% quarter-over-quarter.
  • 69 funds opened new Guardant Health positions in Q2 2025 and 44 closed out, a net change of +25 holders.
  • The largest Guardant Health buyer in Q2 2025 was Millennium Management, an estimated $72.6M added.
  • The largest Guardant Health seller in Q2 2025 was Cadian Capital Management, an estimated $63.2M sold.

Based on aggregated 13F filings for Q2 2025.