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Guardant Health
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Overview Fund Activity

338 hedge funds and large institutions have $5.05B invested in Guardant Health in 2025 Q1 according to their latest regulatory filings, with 90 funds opening new positions, 90 increasing their positions, 108 reducing their positions, and 46 closing their positions.

Holders
338
Holders Change
+42
Holders Change %
+14.19%
% of All Funds
4.59%
Holding in Top 10
6
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.08%
New
90
Increased
90
Reduced
108
Closed
46
Calls
$69.7M
Puts
$102M
Net Calls
-$32.4M
Net Calls Change
-$5.19M

Top Buyers

1
Citadel Advisors
1
Citadel Advisors
Florida
$153M
2
DCM
2
Driehaus Capital Management
Illinois
$82.3M
3
Invesco
3
Invesco
Georgia
$119M
4
Lord, Abbett & Co
4
Lord, Abbett & Co
New Jersey
$40.7M
5
Capital International Investors
5
Capital International Investors
California
$219M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$85M
2
B
2
Braidwell
Connecticut
$56.5M
3
Fidelity International
3
Fidelity International
Bermuda
$0
4
DTC
4
Deep Track Capital
Connecticut
$232M
5
Man Group
5
Man Group
United Kingdom
$2.82M
Name Market Value Shares Shares
Change 		Shares
Change %
Millennium Management
26
Millennium Management
New York
$46.7M 1,096,733 -130,077 -11%
Voloridge Investment Management
27
Voloridge Investment Management
Florida
$44.8M 1,050,821 +454,139 +76%
Temasek Holdings
28
Temasek Holdings
Singapore
$44.5M 1,044,097 -517,882 -33%
Charles Schwab
29
Charles Schwab
California
$42.5M 996,506 -20,027 -2%
AAP
30
Aristotle Atlantic Partners
Florida
$41.1M 964,521 +112,526 +13%
Lord, Abbett & Co
31
Lord, Abbett & Co
New Jersey
$40.7M 954,493 +954,493 New
Morgan Stanley
32
Morgan Stanley
New York
$40.1M 940,505 -491,911 -34%
Bank of New York Mellon
33
Bank of New York Mellon
New York
$36.3M 852,052 -47,850 -5%
Federated Hermes
34
Federated Hermes
Pennsylvania
$36.2M 850,009 -112,713 -12%
Adage Capital Partners
35
Adage Capital Partners
Massachusetts
$36.1M 846,749 +566,949 +203%
Balyasny Asset Management
36
Balyasny Asset Management
Illinois
$35.7M 838,992 -153,546 -15%
Point72 Asset Management
37
Point72 Asset Management
Connecticut
$33.1M 776,570 -96,512 -11%
Deutsche Bank
38
Deutsche Bank
Germany
$31.8M 746,636 -30,534 -4%
BWLSA
39
Blue Water Life Science Advisors
California
$29.6M 694,047 – –
EAM
40
Erste Asset Management
Austria
$27.2M 638,600 -54,000 -8%
T. Rowe Price Associates
41
T. Rowe Price Associates
Maryland
$26.8M 629,508 +533,104 +553%
RPI
42
Railway Pension Investments
United Kingdom
$26.4M 620,878 – –
Renaissance Technologies
43
Renaissance Technologies
New York
$26.3M 616,500 +113,400 +23%
ITP
44
Iron Triangle Partners
Connecticut
$25.6M 600,867 +600,867 New
Manulife (Manufacturers Life Insurance)
45
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$24.6M 578,346 +95,458 +20%
EA
46
Emerald Advisers
Pennsylvania
$22.6M 531,424 +531,424 New
PAMP
47
Polar Asset Management Partners
Ontario, Canada
$22.4M 525,702 +71,202 +16%
Principal Financial Group
48
Principal Financial Group
Iowa
$21.2M 498,129 +488,043 +4,839%
Fidelity Investments
49
Fidelity Investments
Massachusetts
$20.9M 489,929 -669,682 -58%
Bank of America
50
Bank of America
North Carolina
$20.7M 486,365 +26,754 +6%
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