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Guardant Health

394 hedge funds and large institutions have $7.65B invested in Guardant Health in 2025 Q3 according to their latest regulatory filings, with 71 funds opening new positions, 134 increasing their positions, 132 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

82% more first-time investments, than exits

New positions opened: 71 | Existing positions closed: 39

50% more funds holding in top 10

Funds holding in top 10: 69 (+3)

18% more capital invested

Capital invested by funds: $6.47B → $7.65B (+$1.19B)

8% more funds holding

Funds holding: 364394 (+30)

2% more repeat investments, than reductions

Existing positions increased: 134 | Existing positions reduced: 132

10% less call options, than puts

Call options by funds: $156M | Put options by funds: $173M

2.09% less ownership

Funds ownership: 100.34%98.24% (-2.1%)

Holders
394
Holders Change
+30
Holders Change %
+8.24%
% of All Funds
5.17%
Holding in Top 10
9
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+50%
% of All Funds
0.12%
New
71
Increased
134
Reduced
132
Closed
39
Calls
$156M
Puts
$173M
Net Calls
-$16.8M
Net Calls Change
+$20.6M
Name Holding Trade Value Shares
Change
Change in
Stake
OQS
276
Occudo Quantitative Strategies
Florida
$249K -$281K -5,166 -56%
JCM
277
Jag Capital Management
Missouri
$248K +$216K +3,973 New
CIBC Asset Management
278
CIBC Asset Management
Ontario, Canada
$246K
Mariner
279
Mariner
Kansas
$245K -$151K -2,779 -41%
AB
280
Amalgamated Bank
New York
$242K -$13.8K -254 -6%
Mercer Global Advisors
281
Mercer Global Advisors
Colorado
$242K +$210K +3,867 New
EI
282
Ethic Inc
New York
$241K -$22.1K -406 -10%
AI
283
Atria Investments
North Carolina
$238K -$10.8K -198 -5%
AHL
284
Abel Hall LLC
Louisiana
$236K -$5.44K -100 -3%
WANY
285
Wealthspire Advisors (New York)
New York
$228K +$199K +3,651 New
VanEck Associates
286
VanEck Associates
New York
$227K +$43.5K +799 +28%
XT
287
XTX Topco
Cayman Islands
$222K +$193K +3,547 New
Nisa Investment Advisors
288
Nisa Investment Advisors
Missouri
$221K
NS
289
NBC Securities
Alabama
$216K +$83K +1,525 +79%
Fidelity International
290
Fidelity International
Bermuda
$207K +$181K +3,321 New
KBC Group
291
KBC Group
Belgium
$196K
GFM
292
GF Fund Management
China
$168K -$26.2K -481 -15%
TRCT
293
Tower Research Capital (TRC)
New York
$163K -$679K -12,482 -83%
DJSG
294
D.J. St. Germain
Massachusetts
$155K +$135K +2,479 New
Northwestern Mutual Wealth Management
295
Northwestern Mutual Wealth Management
Wisconsin
$147K
SS
296
SBI Securities
Japan
$130K +$39.1K +718 +53%
LSA
297
Leonteq Securities AG
Switzerland
$127K +$870 +16 +0.8%
EB
298
Eastern Bank
Massachusetts
$126K +$110K +2,021 New
Carson Wealth (CWM LLC)
299
Carson Wealth (CWM LLC)
Nebraska
$126K +$19.5K +359 +22%
BG
300
Bellevue Group
Switzerland
$122K +$106K +1,953 New

GH Hedge Fund Activity: Q3 2025 in Review

394 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q3 2025, worth a combined $7.65B — up 18% from $6.47B a quarter earlier.

Buyers outnumbered sellers: 71 funds opened new GH positions and 39 closed out — a net gain of 32 holders — while 134 added to existing stakes and 132 trimmed.

The largest buyer was T. Rowe Price Associates, adding an estimated $134M. The largest seller was Citadel Advisors, cutting an estimated $143M.

  • 394 institutional investors held Guardant Health (GH) as of Q3 2025, up from 364 in Q2 2025.
  • Funds reported $7.65B of Guardant Health stock for Q3 2025, up 18% quarter-over-quarter.
  • 71 funds opened new Guardant Health positions in Q3 2025 and 39 closed out, a net change of +32 holders.
  • The largest Guardant Health buyer in Q3 2025 was T. Rowe Price Associates, an estimated $134M added.
  • The largest Guardant Health seller in Q3 2025 was Citadel Advisors, an estimated $143M sold.

Based on aggregated 13F filings for Q3 2025.