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Guardant Health

394 hedge funds and large institutions have $7.65B invested in Guardant Health in 2025 Q3 according to their latest regulatory filings, with 71 funds opening new positions, 134 increasing their positions, 132 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

82% more first-time investments, than exits

New positions opened: 71 | Existing positions closed: 39

50% more funds holding in top 10

Funds holding in top 10: 69 (+3)

18% more capital invested

Capital invested by funds: $6.47B → $7.65B (+$1.19B)

8% more funds holding

Funds holding: 364394 (+30)

2% more repeat investments, than reductions

Existing positions increased: 134 | Existing positions reduced: 132

10% less call options, than puts

Call options by funds: $156M | Put options by funds: $173M

2.09% less ownership

Funds ownership: 100.34%98.24% (-2.1%)

Holders
394
Holders Change
+30
Holders Change %
+8.24%
% of All Funds
5.17%
Holding in Top 10
9
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+50%
% of All Funds
0.12%
New
71
Increased
134
Reduced
132
Closed
39
Calls
$156M
Puts
$173M
Net Calls
-$16.8M
Net Calls Change
+$20.6M
Name Holding Trade Value Shares
Change
Change in
Stake
X
226
Xponance
Pennsylvania
$589K +$4.73K +87 +0.9%
Truist Financial
227
Truist Financial
North Carolina
$569K -$21.6K -397 -4%
SCM
228
Semanteon Capital Management
Massachusetts
$568K +$495K +9,097 New
Cetera Investment Advisers
229
Cetera Investment Advisers
Illinois
$563K +$219K +4,029 +81%
VPIM
230
Vanguard Personalized Indexing Management
California
$561K +$39.1K +718 +9%
GCM
231
Graham Capital Management
Connecticut
$540K -$454K -8,340 -49%
CG
232
Caprock Group
Idaho
$532K +$429K +7,885 New
OAM
233
OP Asset Management
$528K +$460K +8,447 New
WAP
234
Wealthcare Advisory Partners
Pennsylvania
$516K +$1.36K +25 +0.3%
Bank of Montreal
235
Bank of Montreal
Ontario, Canada
$513K
FCM
236
Farallon Capital Management
California
$500K
IC
237
IEQ Capital
California
$498K -$59.7K -1,097 -12%
CH
238
Canton Hathaway
Rhode Island
$497K -$50K -920 -10%
NA
239
Navellier & Associates
Nevada
$484K +$422K +7,754 New
ET
240
Entropy Technologies
New York
$444K -$219K -4,020 -36%
FA
241
Fiduciary Alliance
South Carolina
$443K -$37K -680 -9%
OSAM
242
O'Shaughnessy Asset Management
Connecticut
$434K +$378K +6,944 New
EF
243
Empowered Funds
Pennsylvania
$429K +$42K +772 +13%
LP
244
LMR Partners
United Kingdom
$425K +$370K +6,800 New
GIA
245
Guyasuta Investment Advisors
Pennsylvania
$421K
AWA
246
Alta Wealth Advisors
Massachusetts
$406K +$353K +6,496 New
SA
247
Sanctuary Advisors
Indiana
$393K +$99.6K +1,831 +41%
KeyBank National Association
248
KeyBank National Association
Ohio
$391K +$341K +6,261 New
Commonwealth Equity Services
249
Commonwealth Equity Services
Massachusetts
$387K -$183K -3,366 -35%
ACM
250
ADAR1 Capital Management
Texas
$375K +$326K +6,000 New

GH Hedge Fund Activity: Q3 2025 in Review

394 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Guardant Health (GH) for Q3 2025, worth a combined $7.65B — up 18% from $6.47B a quarter earlier.

Buyers outnumbered sellers: 71 funds opened new GH positions and 39 closed out — a net gain of 32 holders — while 134 added to existing stakes and 132 trimmed.

The largest buyer was T. Rowe Price Associates, adding an estimated $134M. The largest seller was Citadel Advisors, cutting an estimated $143M.

  • 394 institutional investors held Guardant Health (GH) as of Q3 2025, up from 364 in Q2 2025.
  • Funds reported $7.65B of Guardant Health stock for Q3 2025, up 18% quarter-over-quarter.
  • 71 funds opened new Guardant Health positions in Q3 2025 and 39 closed out, a net change of +32 holders.
  • The largest Guardant Health buyer in Q3 2025 was T. Rowe Price Associates, an estimated $134M added.
  • The largest Guardant Health seller in Q3 2025 was Citadel Advisors, an estimated $143M sold.

Based on aggregated 13F filings for Q3 2025.