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4D Molecular Therapeutics

152 hedge funds and large institutions have $471M invested in 4D Molecular Therapeutics in 2026 Q1 according to their latest regulatory filings, with 28 funds opening new positions, 39 increasing their positions, 49 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

17% more capital invested

Capital invested by funds: $402M → $471M (+$69.2M)

5.65% more ownership

Funds ownership: 93.51%99.16% (+5.6%)

8% more first-time investments, than exits

New positions opened: 28 | Existing positions closed: 26

1% less funds holding

Funds holding: 153152 (-1)

20% less repeat investments, than reductions

Existing positions increased: 39 | Existing positions reduced: 49

31% less call options, than puts

Call options by funds: $1.06M | Put options by funds: $1.53M

Holders
152
Holders Change
-1
Holders Change %
-0.65%
% of All Funds
1.87%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
28
Increased
39
Reduced
49
Closed
26
Calls
$1.06M
Puts
$1.53M
Net Calls
-$475K
Net Calls Change
-$1.33M
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$48.9M +$5.32M +611,276 +13%
RCM
2
RA Capital Management
Massachusetts
$47M -$5.25M -603,432 -11%
Goldman Sachs
3
Goldman Sachs
New York
$39.2M -$848K -97,467 -2%
BlackRock
4
BlackRock
New York
$38.6M +$700K +80,427 +2%
NHAS
5
Novo Holdings A/S
Denmark
$34M
BI
6
BVF Inc
California
$26.8M -$15.2M -1,750,000 -38%
State Street
7
State Street
Massachusetts
$25.2M +$165K +18,995 +0.7%
VCM
8
Vanguard Capital Management
Pennsylvania
$20.4M +$19.1M +2,195,578 New
AC
9
Armistice Capital
New York
$18.6M +$557K +64,000 +3%
Adage Capital Partners
10
Adage Capital Partners
Massachusetts
$14.9M +$3.22M +370,000 +30%
Federated Hermes
11
Federated Hermes
Pennsylvania
$13.3M -$1.54M -177,222 -11%
TECP
12
Trails Edge Capital Partners
Georgia
$12.1M +$11.3M +1,302,917 New
Geode Capital Management
13
Geode Capital Management
Massachusetts
$9.92M +$464K +53,320 +5%
Bank of America
14
Bank of America
North Carolina
$9.07M +$1.23M +141,582 +17%
EQF
15
Evergreen Quality Fund
Cayman Islands
$8.86M
Deutsche Bank
16
Deutsche Bank
Germany
$6.59M +$33.4K +3,837 +0.5%
Renaissance Technologies
17
Renaissance Technologies
New York
$5.38M +$569K +65,365 +13%
N
18
Nuveen
North Carolina
$5.23M +$3.51M +403,036 +254%
VPM
19
Vanguard Portfolio Management
Pennsylvania
$5.17M +$4.84M +555,829 New
PHP
20
Parkman Healthcare Partners
Connecticut
$4.87M +$167K +19,146 +4%
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$4.86M +$1.98M +227,982 +77%
RI
22
RTW Investments
New York
$4.43M
PBM
23
Propel Bio Management
California
$3.58M +$3.31M +380,420 New
JP Morgan Chase
24
JP Morgan Chase
New York
$3.56M +$1.18M +136,150 +49%
Morgan Stanley
25
Morgan Stanley
New York
$3.22M -$2.85M -327,285 -49%

FDMT Hedge Fund Activity: Q1 2026 in Review

152 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in 4D Molecular Therapeutics (FDMT) for Q1 2026, worth a combined $471M — up 17% from $402M a quarter earlier.

Buyers outnumbered sellers: 28 funds opened new FDMT positions and 26 closed out — a net gain of 2 holders — while 39 added to existing stakes and 49 trimmed.

The largest buyer was Trails Edge Capital Partners, opening a new position worth an estimated $11.3M. The largest seller was BVF Inc, cutting an estimated $15.2M.

  • 152 institutional investors held 4D Molecular Therapeutics (FDMT) as of Q1 2026, down from 153 in Q4 2025.
  • Funds reported $471M of 4D Molecular Therapeutics stock for Q1 2026, up 17% quarter-over-quarter.
  • 28 funds opened new 4D Molecular Therapeutics positions in Q1 2026 and 26 closed out, a net change of +2 holders.
  • The largest 4D Molecular Therapeutics buyer in Q1 2026 was Trails Edge Capital Partners, an estimated $11.3M added.
  • The largest 4D Molecular Therapeutics seller in Q1 2026 was BVF Inc, an estimated $15.2M sold.

Based on aggregated 13F filings for Q1 2026.