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4D Molecular Therapeutics

153 hedge funds and large institutions have $402M invested in 4D Molecular Therapeutics in 2025 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 56 increasing their positions, 37 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

310% more call options, than puts

Call options by funds: $1.13M | Put options by funds: $275K

167% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 12

51% more repeat investments, than reductions

Existing positions increased: 56 | Existing positions reduced: 37

16% more capital invested

Capital invested by funds: $346M → $402M (+$55.9M)

14% more funds holding

Funds holding: 134153 (+19)

8.82% more ownership

Funds ownership: 84.68%93.51% (+8.8%)

Holders
153
Holders Change
+19
Holders Change %
+14.18%
% of All Funds
1.86%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
32
Increased
56
Reduced
37
Closed
12
Calls
$1.13M
Puts
$275K
Net Calls
+$853K
Net Calls Change
-$77K
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$42.4M +$11.1M +1,090,000 +24%
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$34.7M +$29.2M +2,882,508 +164%
BI
3
BVF Inc
California
$34.7M
Goldman Sachs
4
Goldman Sachs
New York
$32.3M +$1.77M +174,489 +4%
BlackRock
5
BlackRock
New York
$30.5M +$1.99M +195,746 +5%
NHAS
6
Novo Holdings A/S
Denmark
$27.4M +$16.7M +1,650,737 +83%
Vanguard Group
7
Vanguard Group
Pennsylvania
$23.2M +$5.26M +518,405 +20%
State Street
8
State Street
Massachusetts
$20.2M +$18.1M +1,785,106 +198%
AC
9
Armistice Capital
New York
$14.5M +$8.52M +840,000 +77%
Federated Hermes
10
Federated Hermes
Pennsylvania
$12.1M +$149K +14,650 +0.9%
Point72 Asset Management
11
Point72 Asset Management
Connecticut
$11.5M +$15.6M +1,539,860 New
Adage Capital Partners
12
Adage Capital Partners
Massachusetts
$9.26M +$10.8M +1,060,156 +606%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$7.59M +$999K +98,506 +11%
EQF
14
Evergreen Quality Fund
Cayman Islands
$7.14M +$9.65M +951,474 New
Bank of America
15
Bank of America
North Carolina
$6.24M +$135K +13,325 +2%
Deutsche Bank
16
Deutsche Bank
Germany
$5.28M +$1.63M +160,876 +30%
Morgan Stanley
17
Morgan Stanley
New York
$5.05M -$1.66M -163,216 -20%
Renaissance Technologies
18
Renaissance Technologies
New York
$3.85M +$2.03M +199,714 +64%
PHP
19
Parkman Healthcare Partners
Connecticut
$3.78M +$3.08M +303,431 +152%
ACH
20
ArrowMark Colorado Holdings
Colorado
$3.64M -$190K -18,726 -4%
Raymond James Financial
21
Raymond James Financial
Florida
$3.58M +$63.2K +6,235 +1%
BBA
22
Baker Bros. Advisors
New York
$3.57M +$4.83M +475,737 New
RI
23
RTW Investments
New York
$3.57M +$4.83M +475,737 New
Charles Schwab
24
Charles Schwab
California
$2.65M +$482K +47,534 +16%
Two Sigma Investments
25
Two Sigma Investments
New York
$2.53M +$649K +64,007 +23%