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4D Molecular Therapeutics

125 hedge funds and large institutions have $141M invested in 4D Molecular Therapeutics in 2025 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 32 increasing their positions, 59 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

21% more call options, than puts

Call options by funds: $156K | Put options by funds: $129K

8.27% less ownership

Funds ownership: 101.33%93.06% (-8.3%)

14% less funds holding

Funds holding: 145125 (-20)

46% less repeat investments, than reductions

Existing positions increased: 32 | Existing positions reduced: 59

46% less capital invested

Capital invested by funds: $262M → $141M (-$121M)

54% less first-time investments, than exits

New positions opened: 17 | Existing positions closed: 37

Holders
125
Holders Change
-20
Holders Change %
-13.79%
% of All Funds
1.68%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
17
Increased
32
Reduced
59
Closed
37
Calls
$156K
Puts
$129K
Net Calls
+$27K
Net Calls Change
-$461K
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$14.7M
BI
2
BVF Inc
California
$14.7M +$8.91M +1,890,647 +71%
BlackRock
3
BlackRock
New York
$14.7M -$1.76M -374,169 -8%
Goldman Sachs
4
Goldman Sachs
New York
$13.5M -$502K -106,579 -2%
Vanguard Group
5
Vanguard Group
Pennsylvania
$8.91M -$485K -103,018 -4%
Janus Henderson Group
6
Janus Henderson Group
United Kingdom
$6.87M -$1.7M -360,305 -16%
NHAS
7
Novo Holdings A/S
Denmark
$6.3M +$2.12M +450,000 +30%
Morgan Stanley
8
Morgan Stanley
New York
$5.74M -$407K -86,314 -5%
Millennium Management
9
Millennium Management
New York
$5.28M +$1M +213,264 +15%
Federated Hermes
10
Federated Hermes
Pennsylvania
$4.04M +$5.87M +1,246,419 +33,132%
State Street
11
State Street
Massachusetts
$3.32M -$399K -84,773 -8%
RG
12
Redmile Group
California
$3.22M -$941K -199,675 -17%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$3.11M -$230K -48,893 -5%
JP Morgan Chase
14
JP Morgan Chase
New York
$2.86M +$314K +66,636 +8%
Bank of America
15
Bank of America
North Carolina
$2.26M +$1.48M +313,428 +81%
VA
16
VR Adviser
New York
$2.19M -$10.7M -2,274,771 -77%
Assenagon Asset Management
17
Assenagon Asset Management
Luxembourg
$2.1M -$12.1K -2,574 -0.4%
ACH
18
ArrowMark Colorado Holdings
Colorado
$1.7M -$1.26M -267,328 -34%
Two Sigma Advisers
19
Two Sigma Advisers
New York
$1.58M +$1.71M +364,000 +288%
Two Sigma Investments
20
Two Sigma Investments
New York
$1.49M +$695K +147,464 +47%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
21
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.33M -$221K -47,000 -10%
Acadian Asset Management
22
Acadian Asset Management
Massachusetts
$1.29M +$1.73M +367,317 +1,103%
Northern Trust
23
Northern Trust
Illinois
$1.23M -$281K -59,745 -14%
DC
24
Decheng Capital
California
$1.08M -$304K -64,485 -16%
DekaBank Deutsche Girozentrale
25
DekaBank Deutsche Girozentrale
Germany
$1.08M

FDMT Hedge Fund Activity: Q1 2025 in Review

125 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in 4D Molecular Therapeutics (FDMT) for Q1 2025, worth a combined $141M — down 46% from $262M a quarter earlier.

Sellers outnumbered buyers: 37 funds closed out of FDMT and 17 opened new positions — a net loss of 20 holders — while 59 trimmed existing stakes and 32 added.

The largest buyer was BVF Inc, adding an estimated $8.91M. The largest seller was VR Adviser, cutting an estimated $10.7M.

  • 125 institutional investors held 4D Molecular Therapeutics (FDMT) as of Q1 2025, down from 145 in Q4 2024.
  • Funds reported $141M of 4D Molecular Therapeutics stock for Q1 2025, down 46% quarter-over-quarter.
  • 17 funds opened new 4D Molecular Therapeutics positions in Q1 2025 and 37 closed out, a net change of -20 holders.
  • The largest 4D Molecular Therapeutics buyer in Q1 2025 was BVF Inc, an estimated $8.91M added.
  • The largest 4D Molecular Therapeutics seller in Q1 2025 was VR Adviser, an estimated $10.7M sold.

Based on aggregated 13F filings for Q1 2025.