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Edgewise Therapeutics

192 hedge funds and large institutions have $2.32B invested in Edgewise Therapeutics in 2025 Q1 according to their latest regulatory filings, with 32 funds opening new positions, 68 increasing their positions, 63 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

88% more call options, than puts

Call options by funds: $61.6M | Put options by funds: $32.7M

11% more funds holding in top 10

Funds holding in top 10: 910 (+1)

6.09% more ownership

Funds ownership: 104.55%110.64% (+6.1%)

8% more repeat investments, than reductions

Existing positions increased: 68 | Existing positions reduced: 63

4% less funds holding

Funds holding: 200192 (-8)

12% less capital invested

Capital invested by funds: $2.64B → $2.32B (-$321M)

16% less first-time investments, than exits

New positions opened: 32 | Existing positions closed: 38

Holders
192
Holders Change
-8
Holders Change %
-4%
% of All Funds
2.57%
Holding in Top 10
10
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+11.11%
% of All Funds
0.13%
New
32
Increased
68
Reduced
63
Closed
38
Calls
$61.6M
Puts
$32.7M
Net Calls
+$28.9M
Net Calls Change
+$15.4M
Name Holding Trade Value Shares
Change
Change in
Stake
HIS
201
Harvest Investment Services
Illinois
-$2.12M -79,381 Closed
TI
202
Trexquant Investment
Connecticut
-$2M -74,781 Closed
PAMP
203
Polar Asset Management Partners
Ontario, Canada
-$1.72M -64,279 Closed
BAMCO Inc
204
BAMCO Inc
New York
-$1.6M -60,000 Closed
JF
205
Jump Financial
Illinois
-$1.47M -55,178 Closed
Simplex Trading
206
Simplex Trading
Illinois
-$1.32M -50,130 Closed
Marshall Wace
207
Marshall Wace
United Kingdom
-$798K -29,893 Closed
BHCM
208
Brevan Howard Capital Management
Jersey
-$677K -25,346 Closed
Victory Capital Management
209
Victory Capital Management
Texas
-$576K -21,568 Closed
HF
210
HRT Financial
New York
-$456K -17,113 Closed
PAP
211
Persistent Asset Partners
Hong Kong
-$435K -16,593 Closed
CCM
212
Cinctive Capital Management
New York
-$376K -14,093 Closed
NCM
213
Nantahala Capital Management
Connecticut
-$357K -13,371 Closed
CM
214
Crestline Management
Texas
-$354K -13,268 Closed
OF
215
Optimize Financial
California
-$322K -12,062 Closed
GCP
216
GSA Capital Partners
United Kingdom
-$310K -11,593 Closed
BFG
217
Bleakley Financial Group
New Jersey
-$269K -10,080 Closed
NICM
218
Neo Ivy Capital Management
New York
-$259K -9,720 Closed
JG
219
Jain Global
New York
-$210K -7,850 Closed
PD
220
Point72 (DIFC)
United Arab Emirates
-$184K -6,889 Closed
QT
221
Quantbot Technologies
New York
-$103K -3,855 Closed
MAM
222
Meeder Asset Management
Ohio
-$88.3K -3,307 Closed
ACM
223
Aquatic Capital Management
Illinois
-$77.3K -2,894 Closed
VEA
224
Virtus ETF Advisers
New York
-$67.4K -2,526 Closed
DP
225
Diadema Partners
New Jersey
-$35.7K -1,359 Closed

EWTX Hedge Fund Activity: Q1 2025 in Review

192 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q1 2025, worth a combined $2.32B — down 12% from $2.64B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of EWTX and 32 opened new positions — a net loss of 6 holders — while 63 trimmed existing stakes and 68 added.

The largest buyer was Perceptive Advisors, adding an estimated $101M. The largest seller was Frazier Life Sciences Management, exiting entirely with an estimated $33.9M sold.

  • 192 institutional investors held Edgewise Therapeutics (EWTX) as of Q1 2025, down from 200 in Q4 2024.
  • Funds reported $2.32B of Edgewise Therapeutics stock for Q1 2025, down 12% quarter-over-quarter.
  • 32 funds opened new Edgewise Therapeutics positions in Q1 2025 and 38 closed out, a net change of -6 holders.
  • The largest Edgewise Therapeutics buyer in Q1 2025 was Perceptive Advisors, an estimated $101M added.
  • The largest Edgewise Therapeutics seller in Q1 2025 was Frazier Life Sciences Management, an estimated $33.9M sold.

Based on aggregated 13F filings for Q1 2025.