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Edgewise Therapeutics

192 hedge funds and large institutions have $2.32B invested in Edgewise Therapeutics in 2025 Q1 according to their latest regulatory filings, with 32 funds opening new positions, 68 increasing their positions, 63 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

88% more call options, than puts

Call options by funds: $61.6M | Put options by funds: $32.7M

11% more funds holding in top 10

Funds holding in top 10: 910 (+1)

6.09% more ownership

Funds ownership: 104.55%110.64% (+6.1%)

8% more repeat investments, than reductions

Existing positions increased: 68 | Existing positions reduced: 63

4% less funds holding

Funds holding: 200192 (-8)

12% less capital invested

Capital invested by funds: $2.64B → $2.32B (-$321M)

16% less first-time investments, than exits

New positions opened: 32 | Existing positions closed: 38

Holders
192
Holders Change
-8
Holders Change %
-4%
% of All Funds
2.57%
Holding in Top 10
10
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+11.11%
% of All Funds
0.13%
New
32
Increased
68
Reduced
63
Closed
38
Calls
$61.6M
Puts
$32.7M
Net Calls
+$28.9M
Net Calls Change
+$15.4M
Name Holding Trade Value Shares
Change
Change in
Stake
Osaic Holdings
176
Osaic Holdings
Arizona
$2.66K -$24.7K -943 -89%
RIL
177
Rothschild Investment LLC
Illinois
$2.64K +$787 +30 +33%
BL
178
BFSG LLC
California
$2.2K -$5.25K -200 -67%
Federated Hermes
179
Federated Hermes
Pennsylvania
$1.76K -$708 -27 -25%
SCM
180
Sterling Capital Management
North Carolina
$1.65K
TPCW
181
TD Private Client Wealth
New York
$1.32K +$1.57K +60 New
Carson Wealth (CWM LLC)
182
Carson Wealth (CWM LLC)
Nebraska
$1K +$918 +35 +135%
VCM
183
Versant Capital Management
Arizona
$880
PFBT
184
Parkside Financial Bank & Trust
Missouri
$880 +$1.05K +40 New
Jones Financial Companies
185
Jones Financial Companies
Missouri
$745 +$839 +32 New
PS
186
Principal Securities
Iowa
$721
CFD
187
Creative Financial Designs
Indiana
$682 +$813 +31 New
SC
188
Stephens Consulting
Michigan
$660 +$787 +30 New
SAM
189
Smartleaf Asset Management
Massachusetts
$488
Russell Investments Group
190
Russell Investments Group
United Kingdom
$418 -$867K -33,060 -100%
FFA
191
Farther Finance Advisors
California
$161
IA
192
IFP Advisors
Florida
$66
FLSM
193
Frazier Life Sciences Management
California
-$33.9M -1,271,245 Closed
LGM
194
Logos Global Management
California
-$10.7M -400,000 Closed
CSS
195
Cubist Systematic Strategies
Connecticut
-$5.86M -219,549 Closed
AG
196
Algert Global
California
-$2.94M -110,259 Closed
JGC
197
J. Goldman & Co
New York
-$2.86M -107,278 Closed
Point72 Asset Management
198
Point72 Asset Management
Connecticut
-$2.8M -106,562 Closed
EI
199
EAM Investors
California
-$2.44M -91,333 Closed
Ensign Peak Advisors
200
Ensign Peak Advisors
Utah
-$2.15M -80,509 Closed

EWTX Hedge Fund Activity: Q1 2025 in Review

192 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q1 2025, worth a combined $2.32B — down 12% from $2.64B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of EWTX and 32 opened new positions — a net loss of 6 holders — while 63 trimmed existing stakes and 68 added.

The largest buyer was Perceptive Advisors, adding an estimated $101M. The largest seller was Frazier Life Sciences Management, exiting entirely with an estimated $33.9M sold.

  • 192 institutional investors held Edgewise Therapeutics (EWTX) as of Q1 2025, down from 200 in Q4 2024.
  • Funds reported $2.32B of Edgewise Therapeutics stock for Q1 2025, down 12% quarter-over-quarter.
  • 32 funds opened new Edgewise Therapeutics positions in Q1 2025 and 38 closed out, a net change of -6 holders.
  • The largest Edgewise Therapeutics buyer in Q1 2025 was Perceptive Advisors, an estimated $101M added.
  • The largest Edgewise Therapeutics seller in Q1 2025 was Frazier Life Sciences Management, an estimated $33.9M sold.

Based on aggregated 13F filings for Q1 2025.