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Edgewise Therapeutics

192 hedge funds and large institutions have $2.32B invested in Edgewise Therapeutics in 2025 Q1 according to their latest regulatory filings, with 32 funds opening new positions, 68 increasing their positions, 63 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

88% more call options, than puts

Call options by funds: $61.6M | Put options by funds: $32.7M

11% more funds holding in top 10

Funds holding in top 10: 910 (+1)

6.09% more ownership

Funds ownership: 104.55%110.64% (+6.1%)

8% more repeat investments, than reductions

Existing positions increased: 68 | Existing positions reduced: 63

4% less funds holding

Funds holding: 200192 (-8)

12% less capital invested

Capital invested by funds: $2.64B → $2.32B (-$321M)

16% less first-time investments, than exits

New positions opened: 32 | Existing positions closed: 38

Holders
192
Holders Change
-8
Holders Change %
-4%
% of All Funds
2.57%
Holding in Top 10
10
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+11.11%
% of All Funds
0.13%
New
32
Increased
68
Reduced
63
Closed
38
Calls
$61.6M
Puts
$32.7M
Net Calls
+$28.9M
Net Calls Change
+$15.4M
Name Holding Trade Value Shares
Change
Change in
Stake
Envestnet Asset Management
126
Envestnet Asset Management
Illinois
$339K +$18.9K +721 +5%
Jane Street
127
Jane Street
New York
$325K -$414K -15,800 -52%
Ameriprise
128
Ameriprise
Minnesota
$290K -$247K -9,417 -42%
Creative Planning
129
Creative Planning
Kansas
$288K +$343K +13,073 New
SG Americas Securities
130
SG Americas Securities
New York
$283K +$338K +12,883 New
Group One Trading
131
Group One Trading
Illinois
$278K +$319K +12,155 +2,554%
Rafferty Asset Management
132
Rafferty Asset Management
New York
$269K +$8.16K +311 +3%
ASRS
133
Arizona State Retirement System
Arizona
$268K +$35.1K +1,338 +12%
BCI
134
Brinker Capital Investments
Pennsylvania
$256K -$7.74K -295 -2%
OPS
135
Orion Portfolio Solutions
Nebraska
$256K -$7.74K -295 -2%
Teacher Retirement System of Texas
136
Teacher Retirement System of Texas
Texas
$251K +$7.29K +278 +2%
CIM
137
Contravisory Investment Management
Massachusetts
$225K +$268K +10,209 New
SWA
138
SFMG Wealth Advisors
Texas
$220K
HSBC Holdings
139
HSBC Holdings
United Kingdom
$219K -$23.2K -885 -8%
SC
140
SummitTX Capital
Texas
$213K +$254K +9,664 New
AQR Capital Management
141
AQR Capital Management
Connecticut
$207K +$1.39K +53 +0.6%
A
142
AlphaQuest
New York
$206K +$188K +7,155 +325%
TI
143
Tidal Investments
Wisconsin
$203K +$242K +9,220 New
TRCT
144
Tower Research Capital (TRC)
New York
$175K +$112K +4,284 +117%
AIP
145
Ameritas Investment Partners
Nebraska
$167K
Zurich Cantonal Bank
146
Zurich Cantonal Bank
Switzerland
$156K -$21.5K -818 -10%
KK
147
KLP Kapitalforvaltning
Norway
$150K
VIA
148
Virtus Investment Advisers
Connecticut
$128K +$153K +5,829 New
Royal Bank of Canada
149
Royal Bank of Canada
Ontario, Canada
$126K +$63.1K +2,405 +72%
BNP Paribas Financial Markets
150
BNP Paribas Financial Markets
France
$121K -$723K -27,578 -83%

EWTX Hedge Fund Activity: Q1 2025 in Review

192 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q1 2025, worth a combined $2.32B — down 12% from $2.64B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of EWTX and 32 opened new positions — a net loss of 6 holders — while 63 trimmed existing stakes and 68 added.

The largest buyer was Perceptive Advisors, adding an estimated $101M. The largest seller was Frazier Life Sciences Management, exiting entirely with an estimated $33.9M sold.

  • 192 institutional investors held Edgewise Therapeutics (EWTX) as of Q1 2025, down from 200 in Q4 2024.
  • Funds reported $2.32B of Edgewise Therapeutics stock for Q1 2025, down 12% quarter-over-quarter.
  • 32 funds opened new Edgewise Therapeutics positions in Q1 2025 and 38 closed out, a net change of -6 holders.
  • The largest Edgewise Therapeutics buyer in Q1 2025 was Perceptive Advisors, an estimated $101M added.
  • The largest Edgewise Therapeutics seller in Q1 2025 was Frazier Life Sciences Management, an estimated $33.9M sold.

Based on aggregated 13F filings for Q1 2025.