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Edgewise Therapeutics

178 hedge funds and large institutions have $1.56B invested in Edgewise Therapeutics in 2025 Q2 according to their latest regulatory filings, with 30 funds opening new positions, 88 increasing their positions, 39 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

126% more repeat investments, than reductions

Existing positions increased: 88 | Existing positions reduced: 39

2.23% more ownership

Funds ownership: 110.64%112.87% (+2.2%)

7% less funds holding

Funds holding: 192178 (-14)

20% less funds holding in top 10

Funds holding in top 10: 108 (-2)

27% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 41

33% less call options, than puts

Call options by funds: $775K | Put options by funds: $1.15M

33% less capital invested

Capital invested by funds: $2.32B → $1.56B (-$764M)

Holders
178
Holders Change
-14
Holders Change %
-7.29%
% of All Funds
2.34%
Holding in Top 10
8
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-20%
% of All Funds
0.11%
New
30
Increased
88
Reduced
39
Closed
41
Calls
$775K
Puts
$1.15M
Net Calls
-$374K
Net Calls Change
-$29.3M
Name Holding Trade Value Shares
Change
Change in
Stake
ACM
101
ADAR1 Capital Management
Texas
$524K +$288K +20,000 +100%
Mirae Asset Global ETFs Holdings
102
Mirae Asset Global ETFs Holdings
Hong Kong
$524K -$54.8K -3,798 -9%
PCM
103
Prelude Capital Management
New York
$509K -$161K -11,186 -22%
Wells Fargo
104
Wells Fargo
California
$503K +$46.5K +3,226 +9%
Manulife (Manufacturers Life Insurance)
105
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$502K -$269K -18,660 -33%
Skandinaviska Enskilda Banken (SEB)
106
Skandinaviska Enskilda Banken (SEB)
Sweden
$493K
California State Teachers Retirement System (CalSTRS)
107
California State Teachers Retirement System (CalSTRS)
California
$483K +$12.3K +850 +2%
EGM
108
Engineers Gate Manager
New York
$458K -$20.9K -1,449 -4%
AG
109
Algert Global
California
$455K +$501K +34,723 New
Handelsbanken Fonder
110
Handelsbanken Fonder
Sweden
$376K +$99.5K +6,900 +32%
GCP
111
GSA Capital Partners
United Kingdom
$358K +$393K +27,276 New
ACM
112
Aquatic Capital Management
Illinois
$355K +$390K +27,042 New
N
113
Numerai
California
$293K +$322K +22,353 New
A
114
AlphaQuest
New York
$280K +$174K +12,032 +129%
SC
115
SummitTX Capital
Texas
$280K +$169K +11,716 +121%
CUAMC
116
China Universal Asset Management Company
China
$277K +$30.7K +2,127 +11%
VOYA Investment Management
117
VOYA Investment Management
Georgia
$261K -$3.76M -260,822 -93%
ProShare Advisors
118
ProShare Advisors
Maryland
$248K -$19K -1,315 -7%
PFSRSONJ
119
Police & Firemen's Retirement System of New Jersey
New Jersey
$228K +$27.4K +1,903 +12%
Creative Planning
120
Creative Planning
Kansas
$222K +$55.3K +3,837 +29%
State Board of Administration of Florida Retirement System
121
State Board of Administration of Florida Retirement System
Florida
$221K
PA
122
Profund Advisors
Maryland
$198K -$8.68K -602 -4%
ASRS
123
Arizona State Retirement System
Arizona
$180K +$22.3K +1,544 +13%
BHCM
124
Brevan Howard Capital Management
Jersey
$178K +$196K +13,561 New
NRD
125
Nebula Research & Development
New York
$173K +$191K +13,219 New

EWTX Hedge Fund Activity: Q2 2025 in Review

178 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q2 2025, worth a combined $1.56B — down 33% from $2.32B a quarter earlier.

Sellers outnumbered buyers: 41 funds closed out of EWTX and 30 opened new positions — a net loss of 11 holders — while 39 trimmed existing stakes and 88 added.

The largest buyer was Braidwell, adding an estimated $39.7M. The largest seller was Deep Track Capital, exiting entirely with an estimated $30.8M sold.

  • 178 institutional investors held Edgewise Therapeutics (EWTX) as of Q2 2025, down from 192 in Q1 2025.
  • Funds reported $1.56B of Edgewise Therapeutics stock for Q2 2025, down 33% quarter-over-quarter.
  • 30 funds opened new Edgewise Therapeutics positions in Q2 2025 and 41 closed out, a net change of -11 holders.
  • The largest Edgewise Therapeutics buyer in Q2 2025 was Braidwell, an estimated $39.7M added.
  • The largest Edgewise Therapeutics seller in Q2 2025 was Deep Track Capital, an estimated $30.8M sold.

Based on aggregated 13F filings for Q2 2025.