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Edgewise Therapeutics

192 hedge funds and large institutions have $2.32B invested in Edgewise Therapeutics in 2025 Q1 according to their latest regulatory filings, with 32 funds opening new positions, 68 increasing their positions, 63 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed

88% more call options, than puts

Call options by funds: $61.6M | Put options by funds: $32.7M

11% more funds holding in top 10

Funds holding in top 10: 910 (+1)

6.09% more ownership

Funds ownership: 104.55%110.64% (+6.1%)

8% more repeat investments, than reductions

Existing positions increased: 68 | Existing positions reduced: 63

4% less funds holding

Funds holding: 200192 (-8)

12% less capital invested

Capital invested by funds: $2.64B → $2.32B (-$321M)

16% less first-time investments, than exits

New positions opened: 32 | Existing positions closed: 38

Holders
192
Holders Change
-8
Holders Change %
-4%
% of All Funds
2.57%
Holding in Top 10
10
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+11.11%
% of All Funds
0.13%
New
32
Increased
68
Reduced
63
Closed
38
Calls
$61.6M
Puts
$32.7M
Net Calls
+$28.9M
Net Calls Change
+$15.4M
Name Holding Trade Value Shares
Change
Change in
Stake
IHAM
26
Integral Health Asset Management
New York
$14.8M +$3.28M +125,000 +23%
Dimensional Fund Advisors
27
Dimensional Fund Advisors
Texas
$14.7M -$1.64M -62,424 -9%
Millennium Management
28
Millennium Management
New York
$13.5M -$7.18M -273,850 -31%
Northern Trust
29
Northern Trust
Illinois
$13.3M -$121K -4,614 -0.8%
FCMV
30
Foresite Capital Management VI
California
$12.9M
EAM
31
Eventide Asset Management
Massachusetts
$12.5M +$14.9M +568,310 New
Charles Schwab
32
Charles Schwab
California
$11.5M -$422K -16,098 -3%
Viking Global Investors
33
Viking Global Investors
Connecticut
$10.8M -$19.3M -734,951 -60%
PHP
34
Parkman Healthcare Partners
Connecticut
$9.36M +$1.16M +44,234 +12%
Morgan Stanley
35
Morgan Stanley
New York
$9M -$720K -27,433 -6%
Qube Research & Technologies (QRT)
36
Qube Research & Technologies (QRT)
United Kingdom
$8.75M +$738K +28,131 +8%
OM
37
Opaleye Management
Massachusetts
$8.69M -$2.23M -85,000 -18%
Adage Capital Partners
38
Adage Capital Partners
Massachusetts
$8.58M +$3.94M +150,000 +63%
Deutsche Bank
39
Deutsche Bank
Germany
$8.27M +$2.63M +100,223 +36%
Goldman Sachs
40
Goldman Sachs
New York
$8.07M +$518K +19,753 +6%
RAM
41
Readystate Asset Management
Illinois
$7.95M +$8.92M +339,871 +1,591%
SI
42
Sofinnova Investments
California
$7.53M -$1.59M -60,555 -15%
Aberdeen Group
43
Aberdeen Group
United Kingdom
$6.89M +$3.54M +134,982 +76%
Pictet Asset Management
44
Pictet Asset Management
Switzerland
$6.66M +$33.4K +1,272 +0.4%
TCM
45
Tang Capital Management
California
$6.6M
T. Rowe Price Associates
46
T. Rowe Price Associates
Maryland
$6.49M +$6.97M +265,831 +915%
VOYA Investment Management
47
VOYA Investment Management
Georgia
$6.18M -$89.5K -3,413 -1%
IC
48
Ikarian Capital
Texas
$6.16M +$7.35M +280,000 New
SSA
49
Schonfeld Strategic Advisors
New York
$6.14M +$275K +10,464 +4%
UBS AM
50
UBS AM
Illinois
$6M -$164K -6,268 -2%

EWTX Hedge Fund Activity: Q1 2025 in Review

192 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Edgewise Therapeutics (EWTX) for Q1 2025, worth a combined $2.32B — down 12% from $2.64B a quarter earlier.

Sellers outnumbered buyers: 38 funds closed out of EWTX and 32 opened new positions — a net loss of 6 holders — while 63 trimmed existing stakes and 68 added.

The largest buyer was Perceptive Advisors, adding an estimated $101M. The largest seller was Frazier Life Sciences Management, exiting entirely with an estimated $33.9M sold.

  • 192 institutional investors held Edgewise Therapeutics (EWTX) as of Q1 2025, down from 200 in Q4 2024.
  • Funds reported $2.32B of Edgewise Therapeutics stock for Q1 2025, down 12% quarter-over-quarter.
  • 32 funds opened new Edgewise Therapeutics positions in Q1 2025 and 38 closed out, a net change of -6 holders.
  • The largest Edgewise Therapeutics buyer in Q1 2025 was Perceptive Advisors, an estimated $101M added.
  • The largest Edgewise Therapeutics seller in Q1 2025 was Frazier Life Sciences Management, an estimated $33.9M sold.

Based on aggregated 13F filings for Q1 2025.