We are live on ! Find out more
EQ icon

Equillium

36 hedge funds and large institutions have $54.7M invested in Equillium in 2025 Q4 according to their latest regulatory filings, with 8 funds opening new positions, 15 increasing their positions, 7 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

423% more call options, than puts

Call options by funds: $649K | Put options by funds: $124K

114% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 7

29% more capital invested

Capital invested by funds: $42.4M → $54.7M (+$12.3M)

8.11% more ownership

Funds ownership: 49.84%57.95% (+8.1%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

10% less funds holding

Funds holding: 4036 (-4)

27% less first-time investments, than exits

New positions opened: 8 | Existing positions closed: 11

Holders
36
Holders Change
-4
Holders Change %
-10%
% of All Funds
0.44%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
8
Increased
15
Reduced
7
Closed
11
Calls
$649K
Puts
$124K
Net Calls
+$525K
Net Calls Change
+$213K
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$9.06M +$7.14M +5,862,212 New
ACM
2
ADAR1 Capital Management
Texas
$8.69M +$58.6K +48,090 +0.9%
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$8.26M
DC
4
Decheng Capital
California
$6.89M
WP
5
Woodline Partners
California
$5.43M -$9.59K -7,870 -0.2%
Aberdeen Group
6
Aberdeen Group
United Kingdom
$3.67M +$2.42M +1,987,162 +524%
Balyasny Asset Management
7
Balyasny Asset Management
Illinois
$3.22M +$88.4K +72,602 +4%
Vanguard Group
8
Vanguard Group
Pennsylvania
$2.98M +$739K +606,477 +46%
Renaissance Technologies
9
Renaissance Technologies
New York
$1.14M +$144K +118,303 +19%
CF
10
Cantor Fitzgerald
New York
$872K +$168K +137,643 +32%
Hudson Bay Capital Management
11
Hudson Bay Capital Management
Connecticut
$664K +$183K +150,000 +54%
DP
12
Diadema Partners
New Jersey
$538K +$57.7K +47,393 +16%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$535K +$42K +34,491 +11%
Two Sigma Investments
14
Two Sigma Investments
New York
$503K +$233K +191,606 +144%
IC
15
Ikarian Capital
Texas
$471K -$35K -28,742 -9%
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$288K +$226K +185,669 New
State Street
17
State Street
Massachusetts
$241K +$21.8K +17,900 +13%
BlackRock
18
BlackRock
New York
$195K
Jane Street
19
Jane Street
New York
$156K +$123K +100,850 New
BFM
20
Boothbay Fund Management
New York
$144K -$35K -28,742 -24%
PAP
21
Persistent Asset Partners
Hong Kong
$144K +$29.4K +24,132 +35%
Northern Trust
22
Northern Trust
Illinois
$137K +$65.2K +53,510 +153%
Royal Bank of Canada
23
Royal Bank of Canada
Ontario, Canada
$124K +$97.1K +79,734 New
AC
24
AlphaCore Capital
California
$81.1K
Two Sigma Advisers
25
Two Sigma Advisers
New York
$68.4K +$53.7K +44,100 New

EQ Hedge Fund Activity: Q4 2025 in Review

36 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Equillium (EQ) for Q4 2025, worth a combined $54.7M — up 29% from $42.4M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of EQ and 8 opened new positions — a net loss of 3 holders — while 7 trimmed existing stakes and 15 added.

The largest buyer was Janus Henderson Group, opening a new position worth an estimated $7.14M. The largest seller was Stempoint Capital, exiting entirely with an estimated $2.73M sold.

  • 36 institutional investors held Equillium (EQ) as of Q4 2025, down from 40 in Q3 2025.
  • Funds reported $54.7M of Equillium stock for Q4 2025, up 29% quarter-over-quarter.
  • 8 funds opened new Equillium positions in Q4 2025 and 11 closed out, a net change of -3 holders.
  • The largest Equillium buyer in Q4 2025 was Janus Henderson Group, an estimated $7.14M added.
  • The largest Equillium seller in Q4 2025 was Stempoint Capital, an estimated $2.73M sold.

Based on aggregated 13F filings for Q4 2025.