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Equillium

50 hedge funds and large institutions have $81M invested in Equillium in 2026 Q1 according to their latest regulatory filings, with 19 funds opening new positions, 9 increasing their positions, 11 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

375% more first-time investments, than exits

New positions opened: 19 | Existing positions closed: 4

155% more call options, than puts

Call options by funds: $611K | Put options by funds: $240K

48% more capital invested

Capital invested by funds: $54.7M → $81M (+$26.3M)

39% more funds holding

Funds holding: 3650 (+14)

6.1% more ownership

Funds ownership: 57.95%64.05% (+6.1%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

18% less repeat investments, than reductions

Existing positions increased: 9 | Existing positions reduced: 11

Holders
50
Holders Change
+14
Holders Change %
+38.89%
% of All Funds
0.62%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
19
Increased
9
Reduced
11
Closed
4
Calls
$611K
Puts
$240K
Net Calls
+$371K
Net Calls Change
-$154K
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$13M +$1.04M +632,359 +11%
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$10.7M
DC
3
Decheng Capital
California
$8.89M
ACM
4
ADAR1 Capital Management
Texas
$7.45M -$3.1M -1,881,419 -34%
WP
5
Woodline Partners
California
$7M
Aberdeen Group
6
Aberdeen Group
United Kingdom
$6.71M +$1.62M +986,149 +42%
RCM
7
RA Capital Management
Massachusetts
$6.19M +$5.09M +3,096,336 New
VCM
8
Vanguard Capital Management
Pennsylvania
$3.57M +$2.94M +1,784,472 New
Balyasny Asset Management
9
Balyasny Asset Management
Illinois
$3.28M -$720K -437,480 -21%
EP
10
Eversept Partners
New York
$3M +$2.47M +1,498,993 New
AAA
11
Affinity Asset Advisors
New York
$2.45M +$2.02M +1,226,310 New
Renaissance Technologies
12
Renaissance Technologies
New York
$1.31M -$125K -76,262 -10%
DP
13
Diadema Partners
New Jersey
$868K +$142K +86,451 +25%
Hudson Bay Capital Management
14
Hudson Bay Capital Management
Connecticut
$857K
Geode Capital Management
15
Geode Capital Management
Massachusetts
$758K +$55.1K +33,503 +10%
IC
16
Ikarian Capital
Texas
$607K
CF
17
Cantor Fitzgerald
New York
$525K -$494K -300,000 -53%
Two Sigma Investments
18
Two Sigma Investments
New York
$492K -$129K -78,437 -24%
Jane Street
19
Jane Street
New York
$442K +$198K +120,391 +119%
VFT
20
Vanguard Fiduciary Trust
Pennsylvania
$379K +$312K +189,530 New
State Street
21
State Street
Massachusetts
$348K +$30.7K +18,640 +12%
Citadel Advisors
22
Citadel Advisors
Florida
$317K +$261K +158,733 New
BlackRock
23
BlackRock
New York
$256K +$2.96K +1,799 +1%
Susquehanna International Group
24
Susquehanna International Group
Pennsylvania
$231K -$115K -70,134 -38%
PAP
25
Persistent Asset Partners
Hong Kong
$220K +$28K +16,994 +18%

EQ Hedge Fund Activity: Q1 2026 in Review

50 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Equillium (EQ) for Q1 2026, worth a combined $81M — up 48% from $54.7M a quarter earlier.

Buyers outnumbered sellers: 19 funds opened new EQ positions and 4 closed out — a net gain of 15 holders — while 9 added to existing stakes and 11 trimmed.

The largest buyer was RA Capital Management, opening a new position worth an estimated $5.09M. The largest seller was ADAR1 Capital Management, cutting an estimated $3.1M.

  • 50 institutional investors held Equillium (EQ) as of Q1 2026, up from 36 in Q4 2025.
  • Funds reported $81M of Equillium stock for Q1 2026, up 48% quarter-over-quarter.
  • 19 funds opened new Equillium positions in Q1 2026 and 4 closed out, a net change of +15 holders.
  • The largest Equillium buyer in Q1 2026 was RA Capital Management, an estimated $5.09M added.
  • The largest Equillium seller in Q1 2026 was ADAR1 Capital Management, an estimated $3.1M sold.

Based on aggregated 13F filings for Q1 2026.