Equillium
About: Equillium Inc is a clinical-stage biotechnology company engaged in developing novel therapeutics to treat severe autoimmune and inflammatory, or immuno-inflammatory, disorders with high unmet medical need. The company intends to commercialize its product candidates either independently or through partnerships, or otherwise monetize its pipeline through strategic transactions. Itolizumab (EQ001), a clinical-stage product candidate, is an anti-CD6 immune-modifying monoclonal antibody, or mAb, that selectively targets the CD6-ALCAM signaling pathway to downregulate pathogenic T effector cells while preserving T regulatory cells critical for maintaining a balanced immune response. The company's other clinical-stage and pre-clinical-stage candidates include EQ101 and EQ302.
Employees: 35
Fund manager confidence
Based on 2025 Q1 regulatory disclosures by fund managers ($100M+ AUM)
67% more call options, than puts
Call options by funds: $5K | Put options by funds: $3K
0% more funds holding in top 10
Funds holding in top 10: 2 [Q4 2024] → 2 (+0) [Q1 2025]
0% more repeat investments, than reductions
Existing positions increased: 6 | Existing positions reduced: 6
0.25% less ownership
Funds ownership: 24.57% [Q4 2024] → 24.32% (-0.25%) [Q1 2025]
8% less funds holding
Funds holding: 26 [Q4 2024] → 24 (-2) [Q1 2025]
48% less capital invested
Capital invested by funds: $6.52M [Q4 2024] → $3.39M (-$3.13M) [Q1 2025]
50% less first-time investments, than exits
New positions opened: 2 | Existing positions closed: 4
Research analyst outlook
1 Wall Street Analyst provided 1 year price targets over the past 3 months
1 analyst rating
Leerink Partners Thomas Smith | 188%upside $1 | Market Perform Downgraded | 28 Mar 2025 |
Financial journalist opinion









