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Dyne Therapeutics

197 hedge funds and large institutions have $1.23B invested in Dyne Therapeutics in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 95 increasing their positions, 53 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

79% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 53

20% more funds holding in top 10

Funds holding in top 10: 56 (+1)

5.29% more ownership

Funds ownership: 107.86%113.15% (+5.3%)

5% less capital invested

Capital invested by funds: $1.29B → $1.23B (-$62.7M)

4% less funds holding

Funds holding: 205197 (-8)

23% less first-time investments, than exits

New positions opened: 23 | Existing positions closed: 30

53% less call options, than puts

Call options by funds: $390K | Put options by funds: $823K

Holders
197
Holders Change
-8
Holders Change %
-3.9%
% of All Funds
2.59%
Holding in Top 10
6
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+20%
% of All Funds
0.08%
New
23
Increased
95
Reduced
53
Closed
30
Calls
$390K
Puts
$823K
Net Calls
-$433K
Net Calls Change
-$3.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Marshall Wace
51
Marshall Wace
United Kingdom
$4.26M +$4.93M +447,807 New
PP
52
PDT Partners
New York
$3.67M +$1.77M +161,072 +72%
Royal Bank of Canada
53
Royal Bank of Canada
Ontario, Canada
$3.57M +$4.12M +374,234 +50,916%
IC
54
Ikarian Capital
Texas
$3.46M +$55K +5,000 +1%
TI
55
Trexquant Investment
Connecticut
$3.45M +$307K +27,867 +8%
SSA
56
Schonfeld Strategic Advisors
New York
$3.17M +$2.06M +187,159 +128%
Barclays
57
Barclays
United Kingdom
$3.05M +$983K +89,266 +39%
Deutsche Bank
58
Deutsche Bank
Germany
$3.03M +$10.9K +989 +0.3%
UBS AM
59
UBS AM
Illinois
$2.8M +$1.5M +135,853 +86%
Ameriprise
60
Ameriprise
Minnesota
$2.71M +$859K +78,039 +38%
CSS
61
Cubist Systematic Strategies
Connecticut
$2.65M +$1.79M +162,828 +141%
BNP Paribas Financial Markets
62
BNP Paribas Financial Markets
France
$2.64M +$1.43M +129,894 +88%
Bank of New York Mellon
63
Bank of New York Mellon
New York
$2.57M +$408K +37,038 +16%
Ensign Peak Advisors
64
Ensign Peak Advisors
Utah
$2.53M +$2.71M +245,923 +1,220%
PAI
65
Palo Alto Investors
California
$2.52M -$753K -68,415 -21%
SFM
66
Sphera Funds Management
Israel
$2.11M -$1.19M -107,846 -33%
Schroder Investment Management Group
67
Schroder Investment Management Group
United Kingdom
$1.96M -$410K -37,199 -15%
Neuberger Berman Group
68
Neuberger Berman Group
New York
$1.91M +$2.2M +200,266 New
N
69
Nuveen
North Carolina
$1.9M -$257K -23,384 -10%
TC
70
TwinBeech Capital
New York
$1.88M +$1.53M +138,623 +237%
EAM
71
Exome Asset Management
New York
$1.87M -$688K -62,458 -24%
DekaBank Deutsche Girozentrale
72
DekaBank Deutsche Girozentrale
Germany
$1.85M
Susquehanna International Group
73
Susquehanna International Group
Pennsylvania
$1.77M +$349K +31,661 +21%
Squarepoint
74
Squarepoint
New York
$1.73M +$1.54M +139,896 +334%
DWM
75
Darwin Wealth Management
Florida
$1.64M +$1.33M +120,566 +231%

DYN Hedge Fund Activity: Q2 2025 in Review

197 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Dyne Therapeutics (DYN) for Q2 2025, worth a combined $1.23B — down 4.9% from $1.29B a quarter earlier.

Sellers outnumbered buyers: 30 funds closed out of DYN and 23 opened new positions — a net loss of 7 holders — while 53 trimmed existing stakes and 95 added.

The largest buyer was Adage Capital Partners, opening a new position worth an estimated $35.1M. The largest seller was Citadel Advisors, cutting an estimated $22.7M.

  • 197 institutional investors held Dyne Therapeutics (DYN) as of Q2 2025, down from 205 in Q1 2025.
  • Funds reported $1.23B of Dyne Therapeutics stock for Q2 2025, down 4.9% quarter-over-quarter.
  • 23 funds opened new Dyne Therapeutics positions in Q2 2025 and 30 closed out, a net change of -7 holders.
  • The largest Dyne Therapeutics buyer in Q2 2025 was Adage Capital Partners, an estimated $35.1M added.
  • The largest Dyne Therapeutics seller in Q2 2025 was Citadel Advisors, an estimated $22.7M sold.

Based on aggregated 13F filings for Q2 2025.