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Dyne Therapeutics

197 hedge funds and large institutions have $1.23B invested in Dyne Therapeutics in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 95 increasing their positions, 53 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

79% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 53

20% more funds holding in top 10

Funds holding in top 10: 56 (+1)

5.29% more ownership

Funds ownership: 107.86%113.15% (+5.3%)

5% less capital invested

Capital invested by funds: $1.29B → $1.23B (-$62.7M)

4% less funds holding

Funds holding: 205197 (-8)

23% less first-time investments, than exits

New positions opened: 23 | Existing positions closed: 30

53% less call options, than puts

Call options by funds: $390K | Put options by funds: $823K

Holders
197
Holders Change
-8
Holders Change %
-3.9%
% of All Funds
2.59%
Holding in Top 10
6
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+20%
% of All Funds
0.08%
New
23
Increased
95
Reduced
53
Closed
30
Calls
$390K
Puts
$823K
Net Calls
-$433K
Net Calls Change
-$3.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Morgan Stanley
26
Morgan Stanley
New York
$13M -$324K -29,411 -2%
Goldman Sachs
27
Goldman Sachs
New York
$12.8M +$3.8M +345,557 +35%
VC
28
Vivo Capital
California
$10.6M
O
29
OrbiMed
New York
$9.82M +$185K +16,789 +2%
Citadel Advisors
30
Citadel Advisors
Florida
$8.99M -$22.7M -2,065,515 -69%
Northern Trust
31
Northern Trust
Illinois
$8.01M +$1.31M +118,575 +16%
Qube Research & Technologies (QRT)
32
Qube Research & Technologies (QRT)
United Kingdom
$7.54M +$1.22M +111,151 +16%
Voloridge Investment Management
33
Voloridge Investment Management
Florida
$7.53M -$6.58M -597,305 -43%
FCM
34
Frontier Capital Management
Massachusetts
$7.52M +$5.5M +499,822 +173%
ACH
35
ArrowMark Colorado Holdings
Colorado
$7.33M -$1.41M -127,721 -14%
Charles Schwab
36
Charles Schwab
California
$7.09M +$1M +90,940 +14%
NCM
37
Nantahala Capital Management
Connecticut
$7.09M +$4.4M +400,000 +116%
VPC
38
Vestal Point Capital
New York
$6.93M -$11.8M -1,072,500 -60%
MAM
39
MPM Asset Management
Massachusetts
$6.5M
SI
40
Sofinnova Investments
California
$5.85M -$1.12M -102,031 -14%
JG
41
Jain Global
New York
$5.68M +$6.56M +596,167 New
RSCM
42
Rock Springs Capital Management
Maryland
$5.53M +$622K +56,499 +11%
WP
43
Woodline Partners
California
$5.47M +$4.6K +418 +0.1%
AG
44
Algert Global
California
$5.32M +$913K +82,889 +17%
WA
45
Wasatch Advisors
Utah
$5.31M +$516K +46,889 +9%
CS
46
Candriam SCA
Luxembourg
$4.99M +$669K +60,793 +13%
Bank of America
47
Bank of America
North Carolina
$4.89M +$2.68M +243,825 +90%
D.E. Shaw & Co
48
D.E. Shaw & Co
New York
$4.85M +$2.44M +221,287 +77%
Balyasny Asset Management
49
Balyasny Asset Management
Illinois
$4.65M +$5.38M +488,498 New
Aberdeen Group
50
Aberdeen Group
United Kingdom
$4.61M +$1.86M +169,377 +54%

DYN Hedge Fund Activity: Q2 2025 in Review

197 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Dyne Therapeutics (DYN) for Q2 2025, worth a combined $1.23B — down 4.9% from $1.29B a quarter earlier.

Sellers outnumbered buyers: 30 funds closed out of DYN and 23 opened new positions — a net loss of 7 holders — while 53 trimmed existing stakes and 95 added.

The largest buyer was Adage Capital Partners, opening a new position worth an estimated $35.1M. The largest seller was Citadel Advisors, cutting an estimated $22.7M.

  • 197 institutional investors held Dyne Therapeutics (DYN) as of Q2 2025, down from 205 in Q1 2025.
  • Funds reported $1.23B of Dyne Therapeutics stock for Q2 2025, down 4.9% quarter-over-quarter.
  • 23 funds opened new Dyne Therapeutics positions in Q2 2025 and 30 closed out, a net change of -7 holders.
  • The largest Dyne Therapeutics buyer in Q2 2025 was Adage Capital Partners, an estimated $35.1M added.
  • The largest Dyne Therapeutics seller in Q2 2025 was Citadel Advisors, an estimated $22.7M sold.

Based on aggregated 13F filings for Q2 2025.