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Design Therapeutics
DSGN

Overview Fund Activity

98 hedge funds and large institutions have $133M invested in Design Therapeutics in 2025 Q1 according to their latest regulatory filings, with 14 funds opening new positions, 28 increasing their positions, 36 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
98
Holders Change
+3
Holders Change %
+3.16%
% of All Funds
1.33%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
14
Increased
28
Reduced
36
Closed
10
Calls
$15K
Puts
$17K
Net Calls
-$2K
Net Calls Change
-$14K

Top Buyers

1
KCM
Kynam Capital Management
New Jersey
+$3.49M
2
WP
Woodline Partners
California
+$2.49M
3
TCM
Tang Capital Management
California
+$772K
4
Wellington Management Group
Wellington Management Group
Massachusetts
+$546K
5
DCM
Driehaus Capital Management
Illinois
+$530K

Top Sellers

1
EC
EcoR1 Capital
California
-$2.63M
2
Walleye Capital
Walleye Capital
New York
-$871K
3
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$452K
4
BlackRock
BlackRock
New York
-$385K
5
Morgan Stanley
Morgan Stanley
New York
-$379K
Name Holding Trade Value Shares
Change 		Shares
Change %
SOCM
1
SR One Capital Management
Pennsylvania
$25.2M – – –
LGM
2
Logos Global Management
California
$16.3M – – –
BlackRock
3
BlackRock
New York
$9.57M -$385K -99,636 -4%
FLSM
4
Frazier Life Sciences Management
California
$7.54M – – –
Point72 Asset Management
5
Point72 Asset Management
Connecticut
$7.02M -$150K -38,892 -2%
BBA
6
Baker Bros. Advisors
New York
$6.73M – – –
TCM
7
Tang Capital Management
California
$6.49M +$772K +200,000 +14%
AC
8
Almitas Capital
California
$5.61M +$499K +129,229 +10%
Vanguard Group
9
Vanguard Group
Pennsylvania
$5.51M -$12.7K -3,278 -0.2%
Citadel Advisors
10
Citadel Advisors
Florida
$3.72M +$18K +4,667 +0.5%
Fidelity Investments
11
Fidelity Investments
Massachusetts
$3.66M -$14.8K -3,832 -0.4%
DCM
12
Driehaus Capital Management
Illinois
$3.53M +$530K +137,317 +18%
KCM
13
Kynam Capital Management
New Jersey
$3.49M +$3.49M +904,017 New
Geode Capital Management
14
Geode Capital Management
Massachusetts
$2.99M +$53.5K +13,857 +2%
State Street
15
State Street
Massachusetts
$2.76M -$35.7K -9,245 -1%
WP
16
Woodline Partners
California
$2.49M +$2.49M +645,694 New
Acadian Asset Management
17
Acadian Asset Management
Massachusetts
$2.43M +$244K +63,349 +11%
MB
18
MPM BioImpact
Massachusetts
$2.17M +$13.1K +3,396 +0.6%
D.E. Shaw & Co
19
D.E. Shaw & Co
New York
$1.53M -$452K -117,079 -23%
Northern Trust
20
Northern Trust
Illinois
$1.44M -$55.9K -14,472 -4%
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$1.11M +$283K +73,337 +34%
Goldman Sachs
22
Goldman Sachs
New York
$1.03M -$120K -31,113 -10%
Renaissance Technologies
23
Renaissance Technologies
New York
$1.02M +$44.4K +11,500 +5%
Charles Schwab
24
Charles Schwab
California
$997K -$24.3K -6,300 -2%
Morgan Stanley
25
Morgan Stanley
New York
$957K -$379K -98,305 -28%
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