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Design Therapeutics

92 hedge funds and large institutions have $116M invested in Design Therapeutics in 2025 Q2 according to their latest regulatory filings, with 5 funds opening new positions, 35 increasing their positions, 34 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 34

0.12% more ownership

Funds ownership: 60.71%60.83% (+0.12%)

6% less funds holding

Funds holding: 9892 (-6)

13% less capital invested

Capital invested by funds: $133M → $116M (-$16.6M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

55% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 11

Holders
92
Holders Change
-6
Holders Change %
-6.12%
% of All Funds
1.21%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
5
Increased
35
Reduced
34
Closed
11
Calls
$44K
Puts
Net Calls
+$44K
Net Calls Change
+$46K
Name Holding Trade Value Shares
Change
Change in
Stake
PNC Financial Services Group
76
PNC Financial Services Group
Pennsylvania
$5.63K -$28.4K -7,580 -82%
GFM
77
GF Fund Management
China
$4.88K
AB
78
Amalgamated Bank
New York
$4K
SCM
79
Sterling Capital Management
North Carolina
$2.83K +$1.12K +299 +55%
CA
80
Clearstead Advisors
Ohio
$2.06K
PWMG
81
Private Wealth Management Group
New Jersey
$1.88K
Daiwa Securities Group
82
Daiwa Securities Group
Japan
$1K
Carson Wealth (CWM LLC)
83
Carson Wealth (CWM LLC)
Nebraska
$1K +$599 +160 +144%
PWA
84
Physician Wealth Advisors
Utah
$904 +$1K +268 New
MPWT
85
MassMutual Private Wealth & Trust
Connecticut
$805
EWA
86
EverSource Wealth Advisors
Alabama
$792 +$763 +204 +658%
RA
87
Rise Advisors
New York
$438 +$486 +130 New
IA
88
IFP Advisors
Florida
$155
PD
89
Point72 (DIFC)
United Arab Emirates
$66 +$75 +20 New
BIG
90
Brooklyn Investment Group
New York
$65
FFA
91
Farther Finance Advisors
California
$64
Osaic Holdings
92
Osaic Holdings
Arizona
$34 -$146 -39 -80%
Wellington Management Group
93
Wellington Management Group
Massachusetts
-$546K -141,519 Closed
Millennium Management
94
Millennium Management
New York
-$340K -87,988 Closed
MIM
95
MetLife Investment Management
New Jersey
-$73.2K -18,962 Closed
CF
96
Corebridge Financial
Texas
-$59.4K -15,383 Closed
SG Americas Securities
97
SG Americas Securities
New York
-$50K -12,980 Closed
CA
98
CoreCap Advisors
Michigan
-$11.1K -2,879 Closed
California State Teachers Retirement System (CalSTRS)
99
California State Teachers Retirement System (CalSTRS)
California
-$8.78K -2,275 Closed
CCM
100
Coldstream Capital Management
Washington
-$2.07K -535 Closed

DSGN Hedge Fund Activity: Q2 2025 in Review

92 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Design Therapeutics (DSGN) for Q2 2025, worth a combined $116M — down 13% from $133M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of DSGN and 5 opened new positions — a net loss of 6 holders — while 34 trimmed existing stakes and 35 added.

The largest buyer was Driehaus Capital Management, adding an estimated $609K. The largest seller was Wellington Management Group, exiting entirely with an estimated $546K sold.

  • 92 institutional investors held Design Therapeutics (DSGN) as of Q2 2025, down from 98 in Q1 2025.
  • Funds reported $116M of Design Therapeutics stock for Q2 2025, down 13% quarter-over-quarter.
  • 5 funds opened new Design Therapeutics positions in Q2 2025 and 11 closed out, a net change of -6 holders.
  • The largest Design Therapeutics buyer in Q2 2025 was Driehaus Capital Management, an estimated $609K added.
  • The largest Design Therapeutics seller in Q2 2025 was Wellington Management Group, an estimated $546K sold.

Based on aggregated 13F filings for Q2 2025.