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Design Therapeutics

95 hedge funds and large institutions have $260M invested in Design Therapeutics in 2025 Q3 according to their latest regulatory filings, with 14 funds opening new positions, 17 increasing their positions, 38 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

800% more call options, than puts

Call options by funds: $9K | Put options by funds: $1K

123% more capital invested

Capital invested by funds: $116M → $260M (+$143M)

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

27% more first-time investments, than exits

New positions opened: 14 | Existing positions closed: 11

3% more funds holding

Funds holding: 9295 (+3)

0.26% less ownership

Funds ownership: 60.83%60.57% (-0.26%)

55% less repeat investments, than reductions

Existing positions increased: 17 | Existing positions reduced: 38

Holders
95
Holders Change
+3
Holders Change %
+3.26%
% of All Funds
1.25%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
14
Increased
17
Reduced
38
Closed
11
Calls
$9K
Puts
$1K
Net Calls
+$8K
Net Calls Change
-$36K
Name Holding Trade Value Shares
Change
Change in
Stake
VCIM
51
Velan Capital Investment Management
Georgia
$151K
Wells Fargo
52
Wells Fargo
California
$138K -$9.85K -1,967 -10%
T. Rowe Price Associates
53
T. Rowe Price Associates
Maryland
$123K
Mariner
54
Mariner
Kansas
$121K +$1.71K +341 +2%
Invesco
55
Invesco
Georgia
$110K +$1.13K +225 +2%
IIM
56
INTECH Investment Management
Florida
$107K -$27.6K -5,513 -28%
Susquehanna International Group
57
Susquehanna International Group
Pennsylvania
$106K -$121K -24,147 -63%
AQR Capital Management
58
AQR Capital Management
Connecticut
$103K -$75.4K -15,062 -52%
XT
59
XTX Topco
Cayman Islands
$89.4K +$59.4K +11,868 New
Nisa Investment Advisors
60
Nisa Investment Advisors
Missouri
$89K
Mirae Asset Global ETFs Holdings
61
Mirae Asset Global ETFs Holdings
Hong Kong
$80.8K -$36.2K -7,233 -40%
MIM
62
MetLife Investment Management
New Jersey
$77.7K +$51.7K +10,320 New
PFSRSONJ
63
Police & Firemen's Retirement System of New Jersey
New Jersey
$49.7K
Russell Investments Group
64
Russell Investments Group
United Kingdom
$48K +$13.1K +2,618 +70%
PAS
65
Point72 Asia (Singapore)
Singapore
$42.9K +$28.6K +5,702 New
BNP Paribas Financial Markets
66
BNP Paribas Financial Markets
France
$38.7K +$6.56K +1,310 +34%
CI
67
CAZ Investments
Texas
$37.6K -$12.5K -2,500 -33%
AIP
68
Ameritas Investment Partners
Nebraska
$19.4K
Mirae Asset Global Investments
69
Mirae Asset Global Investments
South Korea
$16.6K +$45 +9 +0.4%
Legal & General Group
70
Legal & General Group
United Kingdom
$15.7K -$5.01K -1,001 -33%
New York State Common Retirement Fund
71
New York State Common Retirement Fund
New York
$15.3K
California State Teachers Retirement System (CalSTRS)
72
California State Teachers Retirement System (CalSTRS)
California
$14.8K +$9.86K +1,969 New
TRCT
73
Tower Research Capital (TRC)
New York
$14.8K -$38.8K -7,739 -80%
PNC Financial Services Group
74
PNC Financial Services Group
Pennsylvania
$13.7K +$761 +152 +9%
SCM
75
Sterling Capital Management
North Carolina
$12.4K +$4.04K +807 +96%

DSGN Hedge Fund Activity: Q3 2025 in Review

95 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Design Therapeutics (DSGN) for Q3 2025, worth a combined $260M — up 123% from $116M a quarter earlier.

Buyers outnumbered sellers: 14 funds opened new DSGN positions and 11 closed out — a net gain of 3 holders — while 17 added to existing stakes and 38 trimmed.

The largest buyer was Point72 Asset Management, adding an estimated $7.68M. The largest seller was Logos Global Management, cutting an estimated $2.82M.

  • 95 institutional investors held Design Therapeutics (DSGN) as of Q3 2025, up from 92 in Q2 2025.
  • Funds reported $260M of Design Therapeutics stock for Q3 2025, up 123% quarter-over-quarter.
  • 14 funds opened new Design Therapeutics positions in Q3 2025 and 11 closed out, a net change of +3 holders.
  • The largest Design Therapeutics buyer in Q3 2025 was Point72 Asset Management, an estimated $7.68M added.
  • The largest Design Therapeutics seller in Q3 2025 was Logos Global Management, an estimated $2.82M sold.

Based on aggregated 13F filings for Q3 2025.