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Design Therapeutics

92 hedge funds and large institutions have $116M invested in Design Therapeutics in 2025 Q2 according to their latest regulatory filings, with 5 funds opening new positions, 35 increasing their positions, 34 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 34

0.12% more ownership

Funds ownership: 60.71%60.83% (+0.12%)

6% less funds holding

Funds holding: 9892 (-6)

13% less capital invested

Capital invested by funds: $133M → $116M (-$16.6M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

55% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 11

Holders
92
Holders Change
-6
Holders Change %
-6.12%
% of All Funds
1.21%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
5
Increased
35
Reduced
34
Closed
11
Calls
$44K
Puts
Net Calls
+$44K
Net Calls Change
+$46K
Name Holding Trade Value Shares
Change
Change in
Stake
VCIM
51
Velan Capital Investment Management
Georgia
$67.4K +$22.5K +6,000 +43%
IIM
52
INTECH Investment Management
Florida
$66.3K -$3.3K -882 -4%
JP Morgan Chase
53
JP Morgan Chase
New York
$61.8K -$3.56K -952 -5%
Mirae Asset Global ETFs Holdings
54
Mirae Asset Global ETFs Holdings
Hong Kong
$60.5K -$2.92K -780 -4%
T. Rowe Price Associates
55
T. Rowe Price Associates
Maryland
$55K +$12.1K +3,245 +25%
Mariner
56
Mariner
Kansas
$53K +$1.01K +269 +2%
KCM
57
Kennedy Capital Management
Missouri
$50.6K +$2.35K +627 +4%
Invesco
58
Invesco
Georgia
$48.4K +$11.3K +3,033 +27%
Citigroup
59
Citigroup
New York
$46K -$34.5K -9,231 -40%
Jacobs Levy Equity Management
60
Jacobs Levy Equity Management
New Jersey
$45.5K -$14.9K -3,981 -23%
Los Angeles Capital Management
61
Los Angeles Capital Management
California
$42.9K +$47.7K +12,735 New
Manulife (Manufacturers Life Insurance)
62
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$40.3K -$3.75K -1,002 -8%
Nisa Investment Advisors
63
Nisa Investment Advisors
Missouri
$39.8K -$344 -92 -0.8%
CUAMC
64
China Universal Asset Management Company
China
$38.4K +$168 +45 +0.4%
TRCT
65
Tower Research Capital (TRC)
New York
$32.7K +$6.72K +1,796 +23%
CI
66
CAZ Investments
Texas
$25.3K -$28.1K -7,500 -50%
PFSRSONJ
67
Police & Firemen's Retirement System of New Jersey
New Jersey
$22.2K
Royal Bank of Canada
68
Royal Bank of Canada
Ontario, Canada
$13K +$3.77K +1,006 +36%
BNP Paribas Financial Markets
69
BNP Paribas Financial Markets
France
$12.9K -$184K -49,049 -93%
Russell Investments Group
70
Russell Investments Group
United Kingdom
$12.7K -$677 -181 -5%
Legal & General Group
71
Legal & General Group
United Kingdom
$10.4K +$1.92K +513 +20%
AIP
72
Ameritas Investment Partners
Nebraska
$8.66K
Mirae Asset Global Investments
73
Mirae Asset Global Investments
South Korea
$7.39K +$1.11K +298 +16%
New York State Common Retirement Fund
74
New York State Common Retirement Fund
New York
$6.83K
Zurich Cantonal Bank
75
Zurich Cantonal Bank
Switzerland
$6.12K -$1.3K -348 -16%

DSGN Hedge Fund Activity: Q2 2025 in Review

92 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Design Therapeutics (DSGN) for Q2 2025, worth a combined $116M — down 13% from $133M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of DSGN and 5 opened new positions — a net loss of 6 holders — while 34 trimmed existing stakes and 35 added.

The largest buyer was Driehaus Capital Management, adding an estimated $609K. The largest seller was Wellington Management Group, exiting entirely with an estimated $546K sold.

  • 92 institutional investors held Design Therapeutics (DSGN) as of Q2 2025, down from 98 in Q1 2025.
  • Funds reported $116M of Design Therapeutics stock for Q2 2025, down 13% quarter-over-quarter.
  • 5 funds opened new Design Therapeutics positions in Q2 2025 and 11 closed out, a net change of -6 holders.
  • The largest Design Therapeutics buyer in Q2 2025 was Driehaus Capital Management, an estimated $609K added.
  • The largest Design Therapeutics seller in Q2 2025 was Wellington Management Group, an estimated $546K sold.

Based on aggregated 13F filings for Q2 2025.