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Design Therapeutics

95 hedge funds and large institutions have $260M invested in Design Therapeutics in 2025 Q3 according to their latest regulatory filings, with 14 funds opening new positions, 17 increasing their positions, 38 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

800% more call options, than puts

Call options by funds: $9K | Put options by funds: $1K

123% more capital invested

Capital invested by funds: $116M → $260M (+$143M)

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

27% more first-time investments, than exits

New positions opened: 14 | Existing positions closed: 11

3% more funds holding

Funds holding: 9295 (+3)

0.26% less ownership

Funds ownership: 60.83%60.57% (-0.26%)

55% less repeat investments, than reductions

Existing positions increased: 17 | Existing positions reduced: 38

Holders
95
Holders Change
+3
Holders Change %
+3.26%
% of All Funds
1.25%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
14
Increased
17
Reduced
38
Closed
11
Calls
$9K
Puts
$1K
Net Calls
+$8K
Net Calls Change
-$36K
Name Holding Trade Value Shares
Change
Change in
Stake
BCM
26
Bridgeway Capital Management
Texas
$1.42M
Morgan Stanley
27
Morgan Stanley
New York
$1.33M -$188K -37,559 -18%
N
28
Nuveen
North Carolina
$1M
Jane Street
29
Jane Street
New York
$887K +$435K +86,754 +279%
Barclays
30
Barclays
United Kingdom
$664K -$107K -21,360 -20%
Bank of New York Mellon
31
Bank of New York Mellon
New York
$659K -$35.7K -7,128 -8%
Millennium Management
32
Millennium Management
New York
$518K +$345K +68,823 New
LCM
33
Lynx1 Capital Management
Puerto Rico
$497K
Two Sigma Investments
34
Two Sigma Investments
New York
$446K -$151K -30,074 -34%
PWM
35
Palumbo Wealth Management
New York
$392K -$42.4K -8,474 -14%
American Century Companies
36
American Century Companies
Missouri
$383K +$22.4K +4,467 +10%
DAM
37
DLD Asset Management
New York
$377K +$250K +50,000 New
RhumbLine Advisers
38
RhumbLine Advisers
Massachusetts
$349K -$9.93K -1,983 -4%
AllianceBernstein
39
AllianceBernstein
Tennessee
$347K +$5.46K +1,090 +2%
Prudential Financial
40
Prudential Financial
New Jersey
$338K -$65.6K -13,100 -23%
Two Sigma Advisers
41
Two Sigma Advisers
New York
$305K -$341K -68,000 -63%
CUAMC
42
China Universal Asset Management Company
China
$263K +$118K +23,580 +207%
HF
43
HRT Financial
New York
$240K +$160K +31,903 New
KCM
44
Kennedy Capital Management
Missouri
$221K +$72.1K +14,401 +96%
State of Wisconsin Investment Board
45
State of Wisconsin Investment Board
Wisconsin
$204K -$8.01K -1,600 -6%
Bank of America
46
Bank of America
North Carolina
$180K -$3.6K -718 -3%
JP Morgan Chase
47
JP Morgan Chase
New York
$175K +$24.5K +4,896 +27%
UBS Group
48
UBS Group
Switzerland
$171K -$23.3K -4,649 -17%
SO
49
STRS Ohio
Ohio
$170K
SFM
50
Sphera Funds Management
Israel
$165K +$110K +21,918 New

DSGN Hedge Fund Activity: Q3 2025 in Review

95 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Design Therapeutics (DSGN) for Q3 2025, worth a combined $260M — up 123% from $116M a quarter earlier.

Buyers outnumbered sellers: 14 funds opened new DSGN positions and 11 closed out — a net gain of 3 holders — while 17 added to existing stakes and 38 trimmed.

The largest buyer was Point72 Asset Management, adding an estimated $7.68M. The largest seller was Logos Global Management, cutting an estimated $2.82M.

  • 95 institutional investors held Design Therapeutics (DSGN) as of Q3 2025, up from 92 in Q2 2025.
  • Funds reported $260M of Design Therapeutics stock for Q3 2025, up 123% quarter-over-quarter.
  • 14 funds opened new Design Therapeutics positions in Q3 2025 and 11 closed out, a net change of +3 holders.
  • The largest Design Therapeutics buyer in Q3 2025 was Point72 Asset Management, an estimated $7.68M added.
  • The largest Design Therapeutics seller in Q3 2025 was Logos Global Management, an estimated $2.82M sold.

Based on aggregated 13F filings for Q3 2025.