|
1
|
Baker Bros. Advisors
New York
|
$14.8M
|
–
|
–
|
–
|
|
|
2
|
Franklin Resources
San Mateo,
California
|
$10.6M
|
–
|
–
|
–
|
|
|
3
|
Broadfin Capital
New York
|
$10.1M
|
–
|
–
|
–
|
|
|
4
|
Jennison Associates
New York
|
$5.57M
|
-$3.56K
|
-953
|
-0.1%
|
|
|
5
|
Granahan Investment Management
Waltham,
Massachusetts
|
$3.94M
|
-$101K
|
-27,100
|
-3%
|
|
|
6
|
Krensavage Asset Management
New York
|
$3.59M
|
+$17.4K
|
+4,657
|
+0.5%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$3.16M
|
+$31.3K
|
+8,376
|
+1%
|
|
|
8
|
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
|
$2.72M
|
+$353K
|
+94,441
|
+16%
|
|
|
9
|
Renaissance Technologies
New York
|
$2.28M
|
+$142K
|
+37,900
|
+7%
|
|
|
10
|
Perceptive Advisors
New York
|
$1.71M
|
–
|
–
|
–
|
|
|
11
|
DAFNA Capital Management
Los Angeles,
California
|
$1.39M
|
–
|
–
|
–
|
|
|
12
|
|
$1.26M
|
-$20.2K
|
-5,394
|
-2%
|
|
|
13
|
Stonepine Capital Management
Bend,
Oregon
|
$1.12M
|
-$839K
|
-224,493
|
-44%
|
|
|
14
|
Royce & Associates
New York
|
$916K
|
-$18.6K
|
-4,986
|
-2%
|
|
|
15
|
Senvest Management
New York
|
$900K
|
-$977K
|
-261,471
|
-53%
|
|
|
16
|
|
$787K
|
-$533K
|
-142,623
|
-42%
|
|
|
17
|
BlackRock Institutional Trust
San Francisco,
California
|
$603K
|
+$13.5K
|
+3,613
|
+2%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$501K
|
-$9.29K
|
-2,487
|
-2%
|
|
|
19
|
Adage Capital Partners
Boston,
Massachusetts
|
$431K
|
-$1.09M
|
-290,673
|
-73%
|
|
|
20
|
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
$364K
|
-$93K
|
-24,899
|
-21%
|
|
|
21
|
Oxford Asset Management
Oxford,
United Kingdom
|
$304K
|
-$176K
|
-47,168
|
-38%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$234K
|
+$25.6K
|
+6,840
|
+13%
|
|
|
23
|
California Public Employees Retirement System
Sacramento,
California
|
$223K
|
–
|
–
|
–
|
|
|
24
|
BlackRock Fund Advisors
San Francisco,
California
|
$215K
|
-$3.2K
|
-856
|
-2%
|
|
|
25
|
Dimensional Fund Advisors
Austin,
Texas
|
$207K
|
+$26.5K
|
+7,086
|
+16%
|
|
