|
1
|
Baker Bros. Advisors
New York
|
$11.6M
|
–
|
–
|
–
|
|
|
2
|
Franklin Resources
San Mateo,
California
|
$8.32M
|
+$218K
|
+65,192
|
+2%
|
|
|
3
|
Broadfin Capital
New York
|
$7.94M
|
–
|
–
|
–
|
|
|
4
|
Jennison Associates
New York
|
$4.38M
|
+$23.4K
|
+6,981
|
+0.5%
|
|
|
5
|
Granahan Investment Management
Waltham,
Massachusetts
|
$3.19M
|
+$168K
|
+50,142
|
+5%
|
|
|
6
|
Krensavage Asset Management
New York
|
$2.81M
|
+$14.1K
|
+4,212
|
+0.5%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.46M
|
+$381K
|
+113,747
|
+17%
|
|
|
8
|
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
|
$1.84M
|
+$707K
|
+210,960
|
+55%
|
|
|
9
|
Renaissance Technologies
New York
|
$1.68M
|
+$343K
|
+102,500
|
+23%
|
|
|
10
|
Stonepine Capital Management
Bend,
Oregon
|
$1.57M
|
–
|
–
|
–
|
|
|
11
|
Senvest Management
New York
|
$1.52M
|
-$2.02M
|
-604,230
|
-55%
|
|
|
12
|
Perceptive Advisors
New York
|
$1.34M
|
+$100K
|
+30,000
|
+7%
|
|
|
13
|
Adage Capital Partners
Boston,
Massachusetts
|
$1.24M
|
–
|
–
|
–
|
|
|
14
|
DAFNA Capital Management
Los Angeles,
California
|
$1.1M
|
–
|
–
|
–
|
|
|
15
|
|
$1.06M
|
+$326K
|
+97,380
|
+40%
|
|
|
16
|
|
$1.01M
|
+$79K
|
+23,591
|
+8%
|
|
|
17
|
Royce & Associates
New York
|
$736K
|
–
|
–
|
–
|
|
|
18
|
BlackRock Institutional Trust
San Francisco,
California
|
$463K
|
–
|
–
|
–
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$401K
|
-$69.8K
|
-20,847
|
-14%
|
|
|
20
|
Roanoke Asset Management
Jersey City,
New Jersey
|
$386K
|
-$390K
|
-116,347
|
-48%
|
|
|
21
|
Oxford Asset Management
Oxford,
United Kingdom
|
$385K
|
-$162K
|
-48,451
|
-28%
|
|
|
22
|
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
$364K
|
+$248K
|
+73,911
|
+170%
|
|
|
23
|
RA Capital Management
Boston,
Massachusetts
|
$252K
|
-$1.88M
|
-559,997
|
-87%
|
|
|
24
|
Credit Suisse
Zurich,
Switzerland
|
$181K
|
+$113K
|
+33,792
|
+138%
|
|
|
25
|
California Public Employees Retirement System
Sacramento,
California
|
$175K
|
–
|
–
|
–
|
|
