|
1
|
Baker Bros. Advisors
New York
|
$17.1M
|
+$1.4M
|
+294,549
|
+9%
|
|
|
2
|
Franklin Resources
San Mateo,
California
|
$12M
|
+$12.4M
|
+2,619,308
|
New
|
|
|
3
|
Broadfin Capital
New York
|
$11.7M
|
+$948K
|
+200,000
|
+8%
|
|
|
4
|
Jennison Associates
New York
|
$6.43M
|
+$1.24M
|
+261,818
|
+23%
|
|
|
5
|
Senvest Management
New York
|
$5M
|
-$278K
|
-58,589
|
-5%
|
|
|
6
|
Granahan Investment Management
Waltham,
Massachusetts
|
$4.47M
|
+$2.24M
|
+473,168
|
+94%
|
|
|
7
|
Consonance Capital Management
New York
|
$4.28M
|
-$4.53M
|
-955,951
|
-50%
|
|
|
8
|
Krensavage Asset Management
New York
|
$4.12M
|
+$4.28M
|
+901,834
|
New
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$3.11M
|
+$428K
|
+90,325
|
+15%
|
|
|
10
|
RA Capital Management
Boston,
Massachusetts
|
$2.93M
|
+$3.04M
|
+641,236
|
New
|
|
|
11
|
Stonepine Capital Management
Bend,
Oregon
|
$2.32M
|
+$2.41M
|
+507,799
|
New
|
|
|
12
|
Renaissance Technologies
New York
|
$2.01M
|
+$751K
|
+158,300
|
+56%
|
|
|
13
|
Perceptive Advisors
New York
|
$1.84M
|
+$201K
|
+42,300
|
+12%
|
|
|
14
|
Adage Capital Partners
Boston,
Massachusetts
|
$1.83M
|
–
|
–
|
–
|
|
|
15
|
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
|
$1.75M
|
+$714K
|
+150,656
|
+65%
|
|
|
16
|
DAFNA Capital Management
Los Angeles,
California
|
$1.62M
|
-$15.2K
|
-3,200
|
-0.9%
|
|
|
17
|
Fidelity International
Hamilton,
Bermuda
|
$1.42M
|
–
|
–
|
–
|
|
|
18
|
|
$1.38M
|
+$478K
|
+100,862
|
+50%
|
|
|
19
|
|
$1.12M
|
+$662K
|
+139,579
|
+132%
|
|
|
20
|
Roanoke Asset Management
Jersey City,
New Jersey
|
$1.1M
|
-$157K
|
-33,030
|
-12%
|
|
|
21
|
Royce & Associates
New York
|
$1.08M
|
+$75.9K
|
+16,000
|
+7%
|
|
|
22
|
AWM Investment Company
New York
|
$864K
|
+$896K
|
+188,995
|
New
|
|
|
23
|
Oxford Asset Management
Oxford,
United Kingdom
|
$783K
|
+$511K
|
+107,821
|
+166%
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$687K
|
+$109K
|
+23,073
|
+18%
|
|
|
25
|
BlackRock Institutional Trust
San Francisco,
California
|
$683K
|
+$290K
|
+61,122
|
+69%
|
|
