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DFTX

Definium Therapeutics
DFTX

190 hedge funds and large institutions have $241M invested in Definium Therapeutics in 2025 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 49 increasing their positions, 47 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

105% more call options, than puts

Call options by funds: $7.79M | Put options by funds: $3.8M

86% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 21

10% more funds holding

Funds holding: 172 → 190 (+18)

4% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 47

0% more funds holding in top 10

Funds holding in top 10: 3 → 3 (0)

1.99% less ownership

Funds ownership: 56.6% → 54.61% (-2%)

17% less capital invested

Capital invested by funds: $289M → $241M (-$48.3M)

Holders
190
Holders Change
+18
Holders Change %
+10.47%
% of All Funds
2.55%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
39
Increased
49
Reduced
47
Closed
21
Calls
$7.79M
Puts
$3.8M
Net Calls
+$3.99M
Net Calls Change
-$5.6M

Top Buyers

Rank Fund Capital Flow
1
RA
Rosalind Advisors
Ontario, Canada
+$3.01M
2
Citadel Advisors
Citadel Advisors
Florida
+$2.09M
3
CC
Commodore Capital
New York
+$1.55M
4
TCM
Tang Capital Management
California
+$1.43M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$1.21M

Top Sellers

Rank Fund Capital Flow
1
TLP
Tri Locum Partners
New York
-$5.71M
2
BlackRock
BlackRock
New York
-$2.54M
3
DTC
Deep Track Capital
Connecticut
-$2.27M
4
Bank of America
Bank of America
North Carolina
-$1.32M
5
Millennium Management
Millennium Management
New York
-$1.29M
Name Holding Trade Value Shares
Change 		Change in
Stake
CIBC Private Wealth Group
151
CIBC Private Wealth Group
Georgia
$2.07K – – –
CWM
152
CarsonAllaria Wealth Management
Illinois
$1.9K +$2.33K +325 New
SS
153
SBI Securities
Japan
$1.79K +$788 +110 +56%
AAP
154
Arax Advisory Partners
Colorado
$1.54K -$86 -12 -4%
CA
155
Continuum Advisory
Idaho
$1.4K – – –
AEPWM
156
Atlantic Edge Private Wealth Management
Florida
$1.13K +$1.38K +193 New
Daiwa Securities Group
157
Daiwa Securities Group
Japan
$1K – – –
NA
158
NewEdge Advisors
Louisiana
$831 -$43 -6 -4%
PW
159
Pandora Wealth
Illinois
$766 +$938 +131 New
Northwestern Mutual Wealth Management
160
Northwestern Mutual Wealth Management
Wisconsin
$585 -$2.64K -368 -79%
HWM
161
HighMark Wealth Management
Minnesota
$585 – – –
SCM
162
Sterling Capital Management
North Carolina
$509 +$93 +13 +18%
AF
163
Allworth Financial
California
$444 – – –
AWM
164
Activest Wealth Management
Florida
$386 – – –
Fifth Third Bancorp
165
Fifth Third Bancorp
Ohio
$345 – – –
EWA
166
EverSource Wealth Advisors
Alabama
$328 +$308 +43 +331%
TCM
167
Tradewinds Capital Management
Washington
$311 – – –
LI
168
Louisbourg Investments
New Brunswick, Canada
$304 – – –
TCM
169
TD Capital Management
Tennessee
$228 +$279 +39 New
ACM
170
Anfield Capital Management
California
$211 – – –
PMFA
171
Plante Moran Financial Advisors
Michigan
$211 – – –
CAM
172
Chesapeake Asset Management
New York
$193 – – –
TCM
173
TruNorth Capital Management
Michigan
$193 – – –
RF
174
Robbins Farley
New Hampshire
$164 – – –
PA
175
Parallel Advisors
California
$111 – – –
5 6
7
8 9

DFTX Hedge Fund Activity: Q1 2025 in Review

190 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Definium Therapeutics (DFTX) for Q1 2025, worth a combined $241M — down 17% from $289M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new DFTX positions and 21 closed out — a net gain of 18 holders — while 49 added to existing stakes and 47 trimmed.

The largest buyer was Rosalind Advisors, opening a new position worth an estimated $3.01M. The largest seller was Tri Locum Partners, exiting entirely with an estimated $5.71M sold.

  • 190 institutional investors held Definium Therapeutics (DFTX) as of Q1 2025, up from 172 in Q4 2024.
  • Funds reported $241M of Definium Therapeutics stock for Q1 2025, down 17% quarter-over-quarter.
  • 39 funds opened new Definium Therapeutics positions in Q1 2025 and 21 closed out, a net change of +18 holders.
  • The largest Definium Therapeutics buyer in Q1 2025 was Rosalind Advisors, an estimated $3.01M added.
  • The largest Definium Therapeutics seller in Q1 2025 was Tri Locum Partners, an estimated $5.71M sold.

Based on aggregated 13F filings for Q1 2025.