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DFTX

Definium Therapeutics

190 hedge funds and large institutions have $241M invested in Definium Therapeutics in 2025 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 49 increasing their positions, 47 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

105% more call options, than puts

Call options by funds: $7.79M | Put options by funds: $3.8M

86% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 21

10% more funds holding

Funds holding: 172190 (+18)

4% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 47

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

1.99% less ownership

Funds ownership: 56.6%54.61% (-2%)

17% less capital invested

Capital invested by funds: $289M → $241M (-$48.3M)

Holders
190
Holders Change
+18
Holders Change %
+10.47%
% of All Funds
2.55%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
39
Increased
49
Reduced
47
Closed
21
Calls
$7.79M
Puts
$3.8M
Net Calls
+$3.99M
Net Calls Change
-$5.6M
Name Holding Trade Value Shares
Change
Change in
Stake
SSG
101
Summit Securities Group
New York
$81.4K +$99.6K +13,911 New
Rafferty Asset Management
102
Rafferty Asset Management
New York
$80.6K +$98.6K +13,773 New
Wealth Enhancement Advisory Services
103
Wealth Enhancement Advisory Services
Minnesota
$79.2K -$86 -12 -0.1%
DC
104
Diametric Capital
Massachusetts
$78.2K -$14.9K -2,080 -13%
PEAK6
105
PEAK6
Illinois
$76.1K +$35.1K +4,907 +61%
HighTower Advisors
106
HighTower Advisors
Illinois
$74.2K -$2.53K -353 -3%
William Blair & Company
107
William Blair & Company
Illinois
$73.1K +$89.5K +12,500 New
AQR Capital Management
108
AQR Capital Management
Connecticut
$71.7K -$92.3K -12,887 -51%
AAS
109
Avantax Advisory Services
Texas
$67.8K +$2.99K +418 +4%
CW
110
CreativeOne Wealth
Kansas
$67K +$82K +11,455 New
TRCT
111
Tower Research Capital (TRC)
New York
$66.5K +$66K +9,218 +429%
SA
112
Sanctuary Advisors
Indiana
$66.3K +$2.36K +330 +3%
S
113
SharpePoint
Arizona
$64K
DWM
114
Diversify Wealth Management
Utah
$63K
SIP
115
Stoneridge Investment Partners
Pennsylvania
$63K
BSG
116
Black Swift Group
Colorado
$62.7K +$76.7K +10,713 New
SEI Investments
117
SEI Investments
Pennsylvania
$60.9K
KK
118
KLP Kapitalforvaltning
Norway
$60.8K
KWMG
119
King Wealth Management Group
Florida
$59K
NSIM
120
North Star Investment Management
Illinois
$55K
CAI
121
Capital Advisors Inc
Oklahoma
$50K +$358K +50,000 New
HCM
122
Hollencrest Capital Management
California
$42.2K
AIP
123
Ameritas Investment Partners
Nebraska
$41.3K
BNP Paribas Financial Markets
124
BNP Paribas Financial Markets
France
$31.6K -$37.5K -5,234 -49%
TWC
125
TD Waterhouse Canada
Ontario, Canada
$27.5K +$4.73K +661 +15%

DFTX Hedge Fund Activity: Q1 2025 in Review

190 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Definium Therapeutics (DFTX) for Q1 2025, worth a combined $241M — down 17% from $289M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new DFTX positions and 21 closed out — a net gain of 18 holders — while 49 added to existing stakes and 47 trimmed.

The largest buyer was Rosalind Advisors, opening a new position worth an estimated $3.01M. The largest seller was Tri Locum Partners, exiting entirely with an estimated $5.71M sold.

  • 190 institutional investors held Definium Therapeutics (DFTX) as of Q1 2025, up from 172 in Q4 2024.
  • Funds reported $241M of Definium Therapeutics stock for Q1 2025, down 17% quarter-over-quarter.
  • 39 funds opened new Definium Therapeutics positions in Q1 2025 and 21 closed out, a net change of +18 holders.
  • The largest Definium Therapeutics buyer in Q1 2025 was Rosalind Advisors, an estimated $3.01M added.
  • The largest Definium Therapeutics seller in Q1 2025 was Tri Locum Partners, an estimated $5.71M sold.

Based on aggregated 13F filings for Q1 2025.