DFTX

Definium Therapeutics

206 hedge funds and large institutions have $909M invested in Definium Therapeutics in 2025 Q4 according to their latest regulatory filings, with 49 funds opening new positions, 91 increasing their positions, 31 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

63% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 30

16.66% more ownership

Funds ownership: 52.23%68.89% (+17%)

6% more funds holding

Funds holding: 194206 (+12)

Holders
206
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$23.4M
Puts
$10.8M
Net Calls
Net Calls Change

Top Buyers

1 +$61.9M
2 +$42.4M
3 +$29.5M
4
BlackRock
BlackRock
New York
+$28.9M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$16.2M

Top Sellers

1 -$15.2M
2 -$8.87M
3 -$7.08M
4
ABG
Ally Bridge Group
New York
-$4.26M
5
Citadel Advisors
Citadel Advisors
Florida
-$1.6M
Name Holding Trade Value Shares
Change
Change in
Stake
KPWS
76
Kestra Private Wealth Services
Texas
$671K
SC
77
Scotia Capital
Ontario, Canada
$664K
Nisa Investment Advisors
78
Nisa Investment Advisors
Missouri
$648K
Simplex Trading
79
Simplex Trading
Illinois
$646K
Squarepoint
80
Squarepoint
New York
$608K
Mirae Asset Global ETFs Holdings
81
Mirae Asset Global ETFs Holdings
Hong Kong
$586K
Citigroup
82
Citigroup
New York
$555K
QCM
83
Quantinno Capital Management
New York
$527K
PWM
84
Palumbo Wealth Management
New York
$522K
PR
85
PSP Research
Pennsylvania
$467K
SRL
86
Scientech Research LLC
New Jersey
$424K
FRM
87
Fox Run Management
Connecticut
$411K
DFCM
88
Dark Forest Capital Management
Puerto Rico
$411K
SSA
89
Schonfeld Strategic Advisors
New York
$408K
RG
90
Rathbones Group
United Kingdom
$404K
IIM
91
INTECH Investment Management
Florida
$397K
New York State Common Retirement Fund
92
New York State Common Retirement Fund
New York
$396K
Manulife (Manufacturers Life Insurance)
93
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$379K
HF
94
HRT Financial
New York
$351K
PFSRSONJ
95
Police & Firemen's Retirement System of New Jersey
New Jersey
$338K
DTL
96
Dynamic Technology Lab
Singapore
$308K
BNP Paribas Financial Markets
97
BNP Paribas Financial Markets
France
$300K
ASRS
98
Arizona State Retirement System
Arizona
$298K
PA
99
Profund Advisors
Maryland
$294K
ProShare Advisors
100
ProShare Advisors
Maryland
$288K