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DFTX

Definium Therapeutics

190 hedge funds and large institutions have $241M invested in Definium Therapeutics in 2025 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 49 increasing their positions, 47 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

105% more call options, than puts

Call options by funds: $7.79M | Put options by funds: $3.8M

86% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 21

10% more funds holding

Funds holding: 172190 (+18)

4% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 47

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

1.99% less ownership

Funds ownership: 56.6%54.61% (-2%)

17% less capital invested

Capital invested by funds: $289M → $241M (-$48.3M)

Holders
190
Holders Change
+18
Holders Change %
+10.47%
% of All Funds
2.55%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
39
Increased
49
Reduced
47
Closed
21
Calls
$7.79M
Puts
$3.8M
Net Calls
+$3.99M
Net Calls Change
-$5.6M
Name Holding Trade Value Shares
Change
Change in
Stake
PWM
76
Palumbo Wealth Management
New York
$132K +$162K +22,628 New
FDCDDQ
77
Federation des caisses Desjardins du Quebec
Quebec, Canada
$131K +$7.16K +1,000 +5%
VOYA Investment Management
78
VOYA Investment Management
Georgia
$124K -$18.3K -2,551 -11%
MMPW
79
Mitchell McLeod Pugh & Williams
Alabama
$117K
Mercer Global Advisors
80
Mercer Global Advisors
Colorado
$115K +$25.6K +3,580 +22%
ProShare Advisors
81
ProShare Advisors
Maryland
$112K -$49.8K -6,958 -27%
PFSRSONJ
82
Police & Firemen's Retirement System of New Jersey
New Jersey
$109K +$29.2K +4,080 +28%
Raymond James Financial
83
Raymond James Financial
Florida
$108K +$17.7K +2,475 +15%
Commonwealth Equity Services
84
Commonwealth Equity Services
Massachusetts
$107K -$22.9K -3,200 -15%
BFM
85
Boothbay Fund Management
New York
$105K
Osaic Holdings
86
Osaic Holdings
Arizona
$103K +$52.1K +7,277 +71%
PA
87
Profund Advisors
Maryland
$102K +$37.4K +5,216 +42%
New York State Common Retirement Fund
88
New York State Common Retirement Fund
New York
$100K
GC
89
Gruss & Co
Florida
$99.1K +$121K +16,939 New
HF
90
HRT Financial
New York
$97K +$120K +16,703 New
SFA
91
Sequoia Financial Advisors
Ohio
$97K
CWM
92
CIBC World Markets
New York
$95.3K +$117K +16,299 New
ASRS
93
Arizona State Retirement System
Arizona
$92.3K -$13.4K -1,864 -11%
Bank of Montreal
94
Bank of Montreal
Ontario, Canada
$88.4K +$31.8K +4,438 +42%
Ameriprise
95
Ameriprise
Minnesota
$88K +$17.5K +2,443 +19%
Teacher Retirement System of Texas
96
Teacher Retirement System of Texas
Texas
$86.9K -$24K -3,345 -18%
CUAMC
97
China Universal Asset Management Company
China
$86K -$6.02K -840 -5%
B
98
Bailard
California
$85.4K
Fidelity Investments
99
Fidelity Investments
Massachusetts
$84.3K -$75.2K -10,497 -42%
Wolverine Trading
100
Wolverine Trading
Illinois
$81.9K -$58.5K -8,170 -38%

DFTX Hedge Fund Activity: Q1 2025 in Review

190 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Definium Therapeutics (DFTX) for Q1 2025, worth a combined $241M — down 17% from $289M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new DFTX positions and 21 closed out — a net gain of 18 holders — while 49 added to existing stakes and 47 trimmed.

The largest buyer was Rosalind Advisors, opening a new position worth an estimated $3.01M. The largest seller was Tri Locum Partners, exiting entirely with an estimated $5.71M sold.

  • 190 institutional investors held Definium Therapeutics (DFTX) as of Q1 2025, up from 172 in Q4 2024.
  • Funds reported $241M of Definium Therapeutics stock for Q1 2025, down 17% quarter-over-quarter.
  • 39 funds opened new Definium Therapeutics positions in Q1 2025 and 21 closed out, a net change of +18 holders.
  • The largest Definium Therapeutics buyer in Q1 2025 was Rosalind Advisors, an estimated $3.01M added.
  • The largest Definium Therapeutics seller in Q1 2025 was Tri Locum Partners, an estimated $5.71M sold.

Based on aggregated 13F filings for Q1 2025.