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DFTX

Definium Therapeutics

190 hedge funds and large institutions have $241M invested in Definium Therapeutics in 2025 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 49 increasing their positions, 47 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

105% more call options, than puts

Call options by funds: $7.79M | Put options by funds: $3.8M

86% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 21

10% more funds holding

Funds holding: 172190 (+18)

4% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 47

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

1.99% less ownership

Funds ownership: 56.6%54.61% (-2%)

17% less capital invested

Capital invested by funds: $289M → $241M (-$48.3M)

Holders
190
Holders Change
+18
Holders Change %
+10.47%
% of All Funds
2.55%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
39
Increased
49
Reduced
47
Closed
21
Calls
$7.79M
Puts
$3.8M
Net Calls
+$3.99M
Net Calls Change
-$5.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Cerity Partners
51
Cerity Partners
New York
$284K +$347K +48,485 New
Simplex Trading
52
Simplex Trading
Illinois
$279K +$270K +37,628 +368%
JP Morgan Chase
53
JP Morgan Chase
New York
$270K -$14.4K -2,013 -4%
UBS AM
54
UBS AM
Illinois
$267K -$282K -39,423 -46%
Mirae Asset Global ETFs Holdings
55
Mirae Asset Global ETFs Holdings
Hong Kong
$255K -$15.3K -2,140 -5%
FC
56
Fore Capital
New York
$234K +$17.6K +2,461 +7%
Invesco
57
Invesco
Georgia
$229K -$16.5K -2,300 -6%
Wells Fargo
58
Wells Fargo
California
$219K -$18.3K -2,558 -6%
MSAM
59
Moloney Securities Asset Management
Missouri
$211K -$577K -80,500 -69%
CF
60
Corebridge Financial
Texas
$211K -$29.2K -4,078 -10%
Janney Montgomery Scott
61
Janney Montgomery Scott
Pennsylvania
$203K +$248K +34,685 New
CC
62
Caxton Corporation
New Jersey
$199K
CCP
63
Clough Capital Partners
Massachusetts
$198K
VF
64
Virtu Financial
New York
$192K +$235K +32,836 New
T. Rowe Price Associates
65
T. Rowe Price Associates
Maryland
$182K -$2.64K -368 -1%
Janus Henderson Group
66
Janus Henderson Group
United Kingdom
$173K
XT
67
XTX Topco
Cayman Islands
$173K -$47.2K -6,595 -18%
Zurich Cantonal Bank
68
Zurich Cantonal Bank
Switzerland
$169K +$12K +1,669 +6%
RG
69
Rathbones Group
United Kingdom
$165K +$57.3K +8,000 +40%
Manulife (Manufacturers Life Insurance)
70
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$160K +$1.83K +256 +0.9%
AG
71
Algert Global
California
$145K +$177K +24,770 New
MCM
72
Massar Capital Management
Connecticut
$144K +$176K +24,583 New
Squarepoint
73
Squarepoint
New York
$137K -$132K -18,497 -44%
VIA
74
Virtus Investment Advisers
Connecticut
$137K +$168K +23,388 New
EC
75
EntryPoint Capital
New York
$133K +$163K +22,708 New

DFTX Hedge Fund Activity: Q1 2025 in Review

190 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Definium Therapeutics (DFTX) for Q1 2025, worth a combined $241M — down 17% from $289M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new DFTX positions and 21 closed out — a net gain of 18 holders — while 49 added to existing stakes and 47 trimmed.

The largest buyer was Rosalind Advisors, opening a new position worth an estimated $3.01M. The largest seller was Tri Locum Partners, exiting entirely with an estimated $5.71M sold.

  • 190 institutional investors held Definium Therapeutics (DFTX) as of Q1 2025, up from 172 in Q4 2024.
  • Funds reported $241M of Definium Therapeutics stock for Q1 2025, down 17% quarter-over-quarter.
  • 39 funds opened new Definium Therapeutics positions in Q1 2025 and 21 closed out, a net change of +18 holders.
  • The largest Definium Therapeutics buyer in Q1 2025 was Rosalind Advisors, an estimated $3.01M added.
  • The largest Definium Therapeutics seller in Q1 2025 was Tri Locum Partners, an estimated $5.71M sold.

Based on aggregated 13F filings for Q1 2025.