|
1
|
Redmile Group
San Francisco,
California
|
$195M
|
-$4.02M
|
-86,324
|
-2%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$177M
|
+$5.23M
|
+112,304
|
+3%
|
|
|
3
|
Franklin Resources
San Mateo,
California
|
$172M
|
+$11.8M
|
+253,895
|
+7%
|
|
|
4
|
|
$156M
|
+$3.5M
|
+75,145
|
+2%
|
|
|
5
|
AllianceBernstein
Nashville,
Tennessee
|
$89.4M
|
+$22.7M
|
+487,445
|
+32%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$83.4M
|
+$1.16M
|
+24,962
|
+1%
|
|
|
7
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$72.2M
|
+$2.8M
|
+60,183
|
+4%
|
|
|
8
|
|
$61.9M
|
+$11.9M
|
+255,200
|
+23%
|
|
|
9
|
New Leaf Venture Partners
New York
|
$54.2M
|
–
|
–
|
–
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$52.4M
|
-$308K
|
-6,624
|
-0.6%
|
|
|
11
|
Consonance Capital Management
New York
|
$44.6M
|
+$23.7M
|
+509,241
|
+105%
|
|
|
12
|
Avoro Capital Advisors
New York
|
$40M
|
-$18.9M
|
-407,000
|
-31%
|
|
|
13
|
Fidelity Investments
Boston,
Massachusetts
|
$35.9M
|
-$30.2M
|
-647,945
|
-45%
|
|
|
14
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$33.2M
|
–
|
–
|
–
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$31.6M
|
+$2.38M
|
+51,224
|
+8%
|
|
|
16
|
Alkeon Capital Management
New York
|
$30.1M
|
–
|
–
|
–
|
|
|
17
|
|
$27.8M
|
+$1.67M
|
+35,940
|
+6%
|
|
|
18
|
Wells Fargo
San Francisco,
California
|
$24.6M
|
-$7.14M
|
-153,397
|
-22%
|
|
|
19
|
Deerfield Management
New York
|
$23.7M
|
–
|
–
|
–
|
|
|
20
|
SV Health Investors
Boston,
Massachusetts
|
$20.2M
|
–
|
–
|
–
|
|
|
21
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$20M
|
+$8.65M
|
+185,876
|
+71%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$19.7M
|
-$792K
|
-17,008
|
-4%
|
|
|
23
|
Janus Henderson Group
London,
|
$19.1M
|
+$4.25M
|
+91,239
|
+27%
|
|
|
24
|
|
$18.3M
|
+$442K
|
+9,484
|
+2%
|
|
|
25
|
Polar Capital Holdings
London,
United Kingdom
|
$17.9M
|
+$2.33M
|
+50,000
|
+14%
|
|
