|
1
|
Redmile Group
San Francisco,
California
|
$293M
|
-$3.39M
|
-71,400
|
-1%
|
|
|
2
|
Franklin Resources
San Mateo,
California
|
$148M
|
+$74.3M
|
+1,562,662
|
+193%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$137M
|
+$36M
|
+757,527
|
+52%
|
|
|
4
|
New Leaf Venture Partners
New York
|
$130M
|
-$47M
|
-988,102
|
-32%
|
|
|
5
|
|
$126M
|
-$114K
|
-2,391
|
-0.1%
|
|
|
6
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$105M
|
-$3.17M
|
-66,594
|
-4%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$105M
|
+$57.8M
|
+1,215,965
|
+256%
|
|
|
8
|
|
$94.2M
|
-$45M
|
-946,400
|
-38%
|
|
|
9
|
AllianceBernstein
Nashville,
Tennessee
|
$78.3M
|
-$4.15M
|
-87,313
|
-6%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$64.4M
|
+$13.4M
|
+281,008
|
+37%
|
|
|
11
|
Farallon Capital Management
San Francisco,
California
|
$59.1M
|
+$9.51M
|
+200,000
|
+27%
|
|
|
12
|
Fidelity Investments
Boston,
Massachusetts
|
$56.7M
|
+$36M
|
+758,042
|
+497%
|
|
|
13
|
Janus Henderson Group
London,
|
$49.7M
|
-$4.61M
|
-97,057
|
-11%
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
$41.2M
|
+$1.96M
|
+41,231
|
+7%
|
|
|
15
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$36.8M
|
+$12.3M
|
+258,717
|
+78%
|
|
|
16
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$35.1M
|
+$4.91M
|
+103,397
|
+22%
|
|
|
17
|
Avoro Capital Advisors
New York
|
$31.1M
|
+$23.8M
|
+500,000
|
New
|
|
|
18
|
Capital World Investors
Los Angeles,
California
|
$30.4M
|
+$10.3M
|
+217,696
|
+81%
|
|
|
19
|
Wells Fargo
San Francisco,
California
|
$30M
|
+$1.64M
|
+34,481
|
+8%
|
|
|
20
|
Polar Capital
London,
United Kingdom
|
$29.6M
|
+$8.06M
|
+169,506
|
+55%
|
|
|
21
|
Cormorant Asset Management
Boston,
Massachusetts
|
$28M
|
-$16.1M
|
-338,500
|
-43%
|
|
|
22
|
SV Health Investors
Boston,
Massachusetts
|
$28M
|
-$4.38M
|
-92,192
|
-17%
|
|
|
23
|
Alkeon Capital Management
New York
|
$26.3M
|
-$20.5M
|
-431,512
|
-51%
|
|
|
24
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$26.3M
|
+$8.17M
|
+171,890
|
+69%
|
|
|
25
|
TimesSquare Capital Management
New York
|
$22.4M
|
+$17.1M
|
+360,415
|
New
|
|
