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Day One Biopharmaceuticals
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Overview Fund Activity

174 hedge funds and large institutions have $560M invested in Day One Biopharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 71 increasing their positions, 56 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
174
Holders Change
-10
Holders Change %
-5.43%
% of All Funds
2.34%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
26
Increased
71
Reduced
56
Closed
34
Calls
$902K
Puts
$581K
Net Calls
+$321K
Net Calls Change
+$855K

Top Buyers

1
BlackRock
1
BlackRock
New York
$63.9M
2
DM
2
Deerfield Management
New York
$24.2M
3
Qube Research & Technologies (QRT)
3
Qube Research & Technologies (QRT)
United Kingdom
$6.14M
4
Renaissance Technologies
4
Renaissance Technologies
New York
$6.5M
5
Morgan Stanley
5
Morgan Stanley
New York
$8.8M

Top Sellers

1
RCM
1
RA Capital Management
Massachusetts
$0
2
ECM
2
Estuary Capital Management
Minnesota
$0
3
Fidelity Investments
3
Fidelity Investments
Massachusetts
$73.7M
4
BCM
4
Boxer Capital Management
California
$0
5
B
5
Braidwell
Connecticut
$14.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
SC
126
Savant Capital
Illinois
$73K -$50.5K -7,769 -41%
EFM
127
E Fund Management
China
$71.4K -$962 -148 -1%
Wealth Enhancement Advisory Services
128
Wealth Enhancement Advisory Services
Minnesota
$69.8K -$6.07K -892 -8%
Prudential Financial
129
Prudential Financial
New Jersey
$69.4K +$69.4K +10,682 New
ET
130
Entropy Technologies
New York
$67.1K +$67.1K +10,330 New
SW
131
SteelPeak Wealth
California
$65K -$37.4K -5,750 -37%
BC
132
BIT Capital
Germany
$54.7K -$703K -108,152 -93%
QT
133
Quantbot Technologies
New York
$49K -$17.9K -2,753 -27%
AIP
134
Ameritas Investment Partners
Nebraska
$47.8K +$14.7K +2,264 +45%
TRCT
135
Tower Research Capital (TRC)
New York
$34.1K +$21.6K +3,326 +173%
Mirae Asset Global Investments
136
Mirae Asset Global Investments
South Korea
$25.5K +$3.41K +525 +15%
TFGT
137
TS Financial Group (TSFG)
Illinois
$22K – – –
QPBE
138
Quintet Private Bank (Europe)
Luxembourg
$21.5K – – –
AP
139
Antipodes Partners
Australia
$19.5K +$6.26K +963 +47%
GFM
140
GF Fund Management
China
$16.8K – – –
FDCDDQ
141
Federation des caisses Desjardins du Quebec
Quebec, Canada
$13.2K – – –
SCM
142
Sterling Capital Management
North Carolina
$12.1K +$11.1K +1,708 +1,162%
AB
143
Amalgamated Bank
New York
$12K – – –
Group One Trading
144
Group One Trading
Illinois
$8.75K -$20.1K -3,098 -70%
Raymond James Financial
145
Raymond James Financial
Florida
$8K +$8K +1,231 New
Nisa Investment Advisors
146
Nisa Investment Advisors
Missouri
$6.8K +$299 +46 +5%
CIAM
147
Caitong International Asset Management
Hong Kong
$5.97K +$5.69K +875 +2,035%
Comerica Bank
148
Comerica Bank
Texas
$5.1K -$1.08K -166 -17%
BNP Paribas Asset Management
149
BNP Paribas Asset Management
France
$5K +$5K +750 New
VCM
150
Versant Capital Management
Arizona
$3.93K +$3.93K +604 New
4 5
6
7 8