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Day One Biopharmaceuticals

168 hedge funds and large institutions have $602M invested in Day One Biopharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 31 funds opening new positions, 53 increasing their positions, 60 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

more funds holding in top 10

Funds holding in top 10:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more capital invested

Capital invested by funds: $ → $

less first-time investments, than exits

New positions opened: | Existing positions closed:

1.61% less ownership

Funds ownership: 85.03%83.42% (-1.6%)

3% less funds holding

Funds holding: 174168 (-6)

12% less repeat investments, than reductions

Existing positions increased: 53 | Existing positions reduced: 60

Holders
168
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$641K
Puts
$432K
Net Calls
Net Calls Change

Top Buyers

1 +$23.8M
2 +$10.7M
3 +$10.2M
4
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$9.76M
5
DM
Deerfield Management
New York
+$6.93M

Top Sellers

1 -$13.7M
2 -$9.51M
3 -$8.78M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$7.35M
5
BlackRock
BlackRock
New York
-$5.84M
Name Holding Trade Value Shares
Change
Change in
Stake
Manulife (Manufacturers Life Insurance)
101
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$180K
BHCM
102
Brevan Howard Capital Management
Jersey
$171K
Zurich Cantonal Bank
103
Zurich Cantonal Bank
Switzerland
$170K
SSA
104
Schonfeld Strategic Advisors
New York
$164K
Capstone Investment Advisors
105
Capstone Investment Advisors
New York
$160K
Janus Henderson Group
106
Janus Henderson Group
United Kingdom
$150K
PFSRSONJ
107
Police & Firemen's Retirement System of New Jersey
New Jersey
$144K
NIM
108
NEOS Investment Management
Connecticut
$138K
TE
109
Tema ETFs
New York
$138K
ASRS
110
Arizona State Retirement System
Arizona
$137K
PCM
111
Polymer Capital Management
New York
$134K
AIM
112
Aigen Investment Management
New York
$133K
CUAMC
113
China Universal Asset Management Company
China
$127K
State Board of Administration of Florida Retirement System
114
State Board of Administration of Florida Retirement System
Florida
$126K
IWC
115
Integrated Wealth Concepts
Massachusetts
$123K
MF
116
Magnetar Financial
Illinois
$116K
AC
117
AXQ Capital
New Jersey
$115K
Teacher Retirement System of Texas
118
Teacher Retirement System of Texas
Texas
$113K
ProShare Advisors
119
ProShare Advisors
Maryland
$112K
QCM
120
Quantinno Capital Management
New York
$104K
OAC
121
OMERS Administration Corp
Ontario, Canada
$103K
Lazard Asset Management
122
Lazard Asset Management
New York
$101K
VOYA Investment Management
123
VOYA Investment Management
Georgia
$93.4K
TRCT
124
Tower Research Capital (TRC)
New York
$92.7K
New York State Common Retirement Fund
125
New York State Common Retirement Fund
New York
$85.5K