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Day One Biopharmaceuticals

184 hedge funds and large institutions have $746M invested in Day One Biopharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 43 funds opening new positions, 69 increasing their positions, 45 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
184
Holders Change
+20
Holders Change %
+12.2%
% of All Funds
2.5%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
43
Increased
69
Reduced
45
Closed
22
Calls
$1.23M
Puts
$1.76M
Net Calls
-$534K
Net Calls Change
+$741K
Name Holding Trade Value Shares
Change
Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$109M +$6.45M +812,981 +6%
BlackRock
2
BlackRock
New York
$53.6M +$4.77M +602,092 +10%
AVLSA
3
Atlas Venture Life Science Advisors
Massachusetts
$51M
Vanguard Group
4
Vanguard Group
Pennsylvania
$47.1M +$748K +94,320 +2%
RCM
5
RA Capital Management
Massachusetts
$45.6M
Alyeska Investment Group
6
Alyeska Investment Group
Illinois
$32.2M +$12.3M +1,547,577 +62%
Franklin Resources
7
Franklin Resources
California
$31.9M +$1.07M +135,418 +3%
Pictet Asset Management
8
Pictet Asset Management
Switzerland
$28.8M +$1.15M +145,516 +4%
B
9
Braidwell
Connecticut
$28M -$10.6M -1,337,000 -27%
ECM
10
Estuary Capital Management
Minnesota
$26.4M -$3.09M -389,928 -10%
DM
11
Deerfield Management
New York
$23.5M +$2.89M +364,707 +14%
State Street
12
State Street
Massachusetts
$21.5M -$3.13M -394,978 -13%
VPC
13
Vestal Point Capital
New York
$20.6M +$9.18M +1,158,127 +80%
PCH
14
Polar Capital Holdings
United Kingdom
$18.6M +$17.2M +2,165,000 +1,170%
Goldman Sachs
15
Goldman Sachs
New York
$12.4M +$8.7M +1,097,679 +232%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$12.2M +$615K +77,483 +5%
Citadel Advisors
17
Citadel Advisors
Florida
$10.6M +$5.77M +727,705 +119%
Millennium Management
18
Millennium Management
New York
$10.5M +$8.95M +1,127,995 +587%
Dimensional Fund Advisors
19
Dimensional Fund Advisors
Texas
$10.3M +$2.98M +375,948 +41%
BCM
20
Boxer Capital Management
California
$9.44M
T. Rowe Price Associates
21
T. Rowe Price Associates
Maryland
$9.3M -$4.23M -533,018 -31%
Hudson Bay Capital Management
22
Hudson Bay Capital Management
Connecticut
$9.12M +$1.83M +230,292 +25%
Bank of America
23
Bank of America
North Carolina
$8.3M +$8.14M +1,026,222 +4,998%
PHP
24
Parkman Healthcare Partners
Connecticut
$8.27M +$339K +42,688 +4%
Marshall Wace
25
Marshall Wace
United Kingdom
$7.04M -$1.67M -210,585 -19%