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Day One Biopharmaceuticals
DAWN

Overview Fund Activity

174 hedge funds and large institutions have $560M invested in Day One Biopharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 71 increasing their positions, 56 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
174
Holders Change
-10
Holders Change %
-5.43%
% of All Funds
2.33%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
26
Increased
71
Reduced
56
Closed
34
Calls
$902K
Puts
$581K
Net Calls
+$321K
Net Calls Change
+$855K

Top Buyers

1
BlackRock
1
BlackRock
New York
$63.9M
2
DM
2
Deerfield Management
New York
$24.2M
3
Qube Research & Technologies (QRT)
3
Qube Research & Technologies (QRT)
United Kingdom
$6.14M
4
Renaissance Technologies
4
Renaissance Technologies
New York
$6.5M
5
Morgan Stanley
5
Morgan Stanley
New York
$8.8M

Top Sellers

1
RCM
1
RA Capital Management
Massachusetts
$0
2
ECM
2
Estuary Capital Management
Minnesota
$0
3
Fidelity Investments
3
Fidelity Investments
Massachusetts
$73.7M
4
BCM
4
Boxer Capital Management
California
$0
5
B
5
Braidwell
Connecticut
$14.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$73.7M -$15.3M -2,357,749 -17%
BlackRock
2
BlackRock
New York
$63.9M +$20M +3,072,502 +45%
AVLSA
3
Atlas Venture Life Science Advisors
Massachusetts
$41.8M – – –
Vanguard Group
4
Vanguard Group
Pennsylvania
$40.1M +$1.52M +233,252 +4%
Franklin Resources
5
Franklin Resources
California
$26.6M +$515K +79,255 +2%
DM
6
Deerfield Management
New York
$24.2M +$4.96M +762,391 +26%
Pictet Asset Management
7
Pictet Asset Management
Switzerland
$24.2M +$566K +87,152 +2%
Alyeska Investment Group
8
Alyeska Investment Group
Illinois
$19.6M -$6.81M -1,047,577 -26%
VPC
9
Vestal Point Capital
New York
$19.5M +$2.61M +401,873 +15%
State Street
10
State Street
Massachusetts
$17.5M -$111K -17,013 -0.6%
B
11
Braidwell
Connecticut
$14.2M -$8.81M -1,355,255 -38%
PCH
12
Polar Capital Holdings
United Kingdom
$13.7M -$1.57M -240,823 -10%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$11.1M +$1.12M +171,964 +11%
Goldman Sachs
14
Goldman Sachs
New York
$11M +$789K +121,368 +8%
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$9.21M +$738K +113,588 +9%
Morgan Stanley
16
Morgan Stanley
New York
$8.8M +$4.18M +643,733 +91%
Hudson Bay Capital Management
17
Hudson Bay Capital Management
Connecticut
$8.43M +$951K +146,300 +13%
Millennium Management
18
Millennium Management
New York
$7.85M -$730K -112,293 -9%
T. Rowe Price Associates
19
T. Rowe Price Associates
Maryland
$7.29M -$341K -52,463 -4%
Renaissance Technologies
20
Renaissance Technologies
New York
$6.5M +$4.24M +652,100 +187%
Bank of America
21
Bank of America
North Carolina
$6.28M -$529K -81,333 -8%
Qube Research & Technologies (QRT)
22
Qube Research & Technologies (QRT)
United Kingdom
$6.14M +$4.31M +663,418 +236%
AG
23
Algert Global
California
$5.89M +$3.48M +534,662 +144%
DCM
24
DAFNA Capital Management
California
$5.71M +$961K +147,800 +20%
EC
25
EcoR1 Capital
California
$5.6M – – –
1
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