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Day One Biopharmaceuticals
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Overview Fund Activity

172 hedge funds and large institutions have $558M invested in Day One Biopharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 71 increasing their positions, 55 reducing their positions, and 34 closing their positions.

Holders
172
Holders Change
-12
Holders Change %
-6.52%
% of All Funds
2.31%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
25
Increased
71
Reduced
55
Closed
34
Calls
$902K
Puts
$581K
Net Calls
+$321K
Net Calls Change
+$855K

Top Buyers

1
BlackRock
1
BlackRock
New York
$63.9M
2
DM
2
Deerfield Management
New York
$24.2M
3
Qube Research & Technologies (QRT)
3
Qube Research & Technologies (QRT)
United Kingdom
$6.14M
4
Renaissance Technologies
4
Renaissance Technologies
New York
$6.5M
5
Morgan Stanley
5
Morgan Stanley
New York
$8.8M

Top Sellers

1
RCM
1
RA Capital Management
Massachusetts
$0
2
ECM
2
Estuary Capital Management
Minnesota
$0
3
Fidelity Investments
3
Fidelity Investments
Massachusetts
$73.7M
4
BCM
4
Boxer Capital Management
California
$0
5
B
5
Braidwell
Connecticut
$14.2M
Name Market Value Shares Shares
Change 		Shares
Change %
Citadel Advisors
26
Citadel Advisors
Florida
$4.57M 703,644 -635,374 -47%
Northern Trust
27
Northern Trust
Illinois
$3.97M 611,161 +75,164 +14%
Charles Schwab
28
Charles Schwab
California
$3.76M 578,763 +50,615 +10%
JGC
29
J. Goldman & Co
New York
$3.62M 557,480 +557,480 New
PHP
30
Parkman Healthcare Partners
Connecticut
$3.25M 500,000 -543,162 -52%
KCM
31
Kennedy Capital Management
Missouri
$2.95M 453,520 +125,829 +38%
SCM
32
Stonepine Capital Management
Oregon
$2.93M 450,000 +101,180 +29%
Point72 Asset Management
33
Point72 Asset Management
Connecticut
$2.54M 391,280 +391,280 New
Barclays
34
Barclays
United Kingdom
$2.26M 348,109 +192,900 +124%
Deutsche Bank
35
Deutsche Bank
Germany
$2.11M 325,288 -9,234 -3%
ECM
36
ExodusPoint Capital Management
New York
$2.08M 320,217 +296,480 +1,249%
Bank of New York Mellon
37
Bank of New York Mellon
New York
$2M 307,853 +59,473 +24%
YIH
38
Y-Intercept (HK)
Hong Kong
$1.83M 281,528 +281,528 New
AQR Capital Management
39
AQR Capital Management
Connecticut
$1.82M 279,850 -338,777 -55%
PL
40
Parkwood LLC
Ohio
$1.79M 275,000 – –
SFI
41
Susquehanna Fundamental Investments
Pennsylvania
$1.71M 263,313 -59,562 -18%
Fisher Asset Management
42
Fisher Asset Management
Washington
$1.44M 221,983 -53,224 -19%
CSS
43
Cubist Systematic Strategies
Connecticut
$1.26M 193,857 +193,857 New
Schroder Investment Management Group
44
Schroder Investment Management Group
United Kingdom
$1.17M 180,133 +180,133 New
UBS AM
45
UBS AM
Illinois
$1.14M 175,416 +63,137 +56%
SFM
46
Sphera Funds Management
Israel
$1.14M 175,371 -159,616 -48%
Royal Bank of Canada
47
Royal Bank of Canada
Ontario, Canada
$1.14M 174,974 -10,759 -6%
Norges Bank
48
Norges Bank
Norway
$1.1M 169,000 +169,000 New
NL
49
Nuveen LLC
North Carolina
$977K 150,372 +10,714 +8%
Russell Investments Group
50
Russell Investments Group
United Kingdom
$932K 143,453 +127,113 +778%
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