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CytomX Therapeutics

121 hedge funds and large institutions have $614M invested in CytomX Therapeutics in 2025 Q4 according to their latest regulatory filings, with 38 funds opening new positions, 39 increasing their positions, 25 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,607% more call options, than puts

Call options by funds: $6.14M | Put options by funds: $360K

90% more first-time investments, than exits

New positions opened: 38 | Existing positions closed: 20

56% more repeat investments, than reductions

Existing positions increased: 39 | Existing positions reduced: 25

40% more capital invested

Capital invested by funds: $438M → $614M (+$175M)

17% more funds holding

Funds holding: 103121 (+18)

1.68% more ownership

Funds ownership: 83.33%85.02% (+1.7%)

Holders
121
Holders Change
+18
Holders Change %
+17.48%
% of All Funds
1.47%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.01%
New
38
Increased
39
Reduced
25
Closed
20
Calls
$6.14M
Puts
$360K
Net Calls
+$5.78M
Net Calls Change
-$26K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$105M +$35.3M +9,291,909 +60%
VA
2
VR Adviser
New York
$66.3M
PA
3
Perceptive Advisors
New York
$41.2M
KCM
4
Kynam Capital Management
New Jersey
$38.2M +$20.2M +5,319,574 +146%
Vanguard Group
5
Vanguard Group
Pennsylvania
$36.1M -$1.79M -472,223 -5%
CC
6
Commodore Capital
New York
$32.8M
Point72 Asset Management
7
Point72 Asset Management
Connecticut
$22.1M +$4.26M +1,120,963 +28%
State Street
8
State Street
Massachusetts
$21.9M +$17.1M +4,495,949 +697%
BBA
9
Baker Bros. Advisors
New York
$18.1M
ACM
10
ADAR1 Capital Management
Texas
$17.8M +$522K +137,355 +3%
Balyasny Asset Management
11
Balyasny Asset Management
Illinois
$16.5M -$155K -40,879 -1%
Financial Engines Advisors
12
Financial Engines Advisors
California
$16.3M +$9.3M +2,447,360 +177%
BlackRock
13
BlackRock
New York
$15.6M +$4.89M +1,287,481 +54%
O
14
OrbiMed
New York
$15M -$18.8M -4,935,850 -58%
IC
15
Ikarian Capital
Texas
$13.5M -$760K -200,000 -6%
VC
16
Vivo Capital
California
$12.3M
EP
17
Eversept Partners
New York
$10.7M +$9.52M +2,507,090 New
Goldman Sachs
18
Goldman Sachs
New York
$10.5M +$7.65M +2,013,191 +450%
WP
19
Woodline Partners
California
$9.96M
Two Sigma Investments
20
Two Sigma Investments
New York
$6.65M +$3.16M +831,057 +114%
Geode Capital Management
21
Geode Capital Management
Massachusetts
$6.5M -$166K -43,632 -3%
Dimensional Fund Advisors
22
Dimensional Fund Advisors
Texas
$5.49M +$3.19M +838,528 +186%
Marshall Wace
23
Marshall Wace
United Kingdom
$4.93M +$197K +51,943 +5%
Qube Research & Technologies (QRT)
24
Qube Research & Technologies (QRT)
United Kingdom
$4.52M +$3.57M +938,628 +766%
SC
25
Stempoint Capital
New York
$4.41M +$3.94M +1,036,311 New