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CytomX Therapeutics
CTMX

Overview Fund Activity

83 hedge funds and large institutions have $303M invested in CytomX Therapeutics in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 26 increasing their positions, 17 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
83
Holders Change
+17
Holders Change %
+25.76%
% of All Funds
1.11%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
29
Increased
26
Reduced
17
Closed
12
Calls
$2.09M
Puts
$362K
Net Calls
+$1.73M
Net Calls Change
+$1.75M

Top Buyers

1
VA
VR Adviser
New York
+$31.7M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$20.7M
3
O
OrbiMed
New York
+$19.2M
4
CC
Commodore Capital
New York
+$17.5M
5
PA
Perceptive Advisors
New York
+$15.9M

Top Sellers

1
Millennium Management
Millennium Management
New York
-$5.89M
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$3.81M
3
BI
BVF Inc
California
-$3.32M
4
CPC
Congress Park Capital
New York
-$1.31M
5
Bank of America
Bank of America
North Carolina
-$1.04M
Name Holding Trade Value Shares
Change 		Shares
Change %
VA
1
VR Adviser
New York
$31.7M +$31.7M +13,969,882 New
TCM
2
Tang Capital Management
California
$25.1M +$9.87M +4,347,837 +65%
Vanguard Group
3
Vanguard Group
Pennsylvania
$21.3M +$9.68M +4,262,418 +83%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$21M +$20.7M +9,130,557 +8,430%
O
5
OrbiMed
New York
$19.2M +$19.2M +8,461,500 New
Point72 Asset Management
6
Point72 Asset Management
Connecticut
$18.4M +$12.3M +5,434,623 +205%
CC
7
Commodore Capital
New York
$17.5M +$17.5M +7,692,300 New
PA
8
Perceptive Advisors
New York
$15.9M +$15.9M +6,993,646 New
Franklin Resources
9
Franklin Resources
California
$13.1M +$13.1M +5,769,230 New
VC
10
Vivo Capital
California
$13.1M +$13.1M +5,769,230 New
FFM
11
Fairmount Funds Management
Pennsylvania
$8.85M +$8.85M +3,896,582 New
PM
12
Prosight Management
Texas
$7.98M -$937K -412,895 -11%
BBA
13
Baker Bros. Advisors
New York
$7.91M +$7.91M +3,484,226 New
RI
14
RTW Investments
New York
$7.86M +$7.86M +3,461,500 New
ACM
15
ADAR1 Capital Management
Texas
$6.99M +$6.89M +3,034,378 +6,451%
Balyasny Asset Management
16
Balyasny Asset Management
Illinois
$6.5M +$6.5M +2,865,625 New
RCM
17
RA Capital Management
Massachusetts
$6.04M +$3.77M +1,661,331 +166%
BlackRock
18
BlackRock
New York
$5.42M +$2.77M +1,222,069 +105%
Marshall Wace
19
Marshall Wace
United Kingdom
$5.34M +$5.15M +2,267,583 +2,651%
WP
20
Woodline Partners
California
$5.3M +$1.54M +679,593 +41%
KCM
21
Kynam Capital Management
New Jersey
$4.89M +$4.89M +2,154,413 New
Renaissance Technologies
22
Renaissance Technologies
New York
$4.23M +$1.6M +706,200 +61%
Geode Capital Management
23
Geode Capital Management
Massachusetts
$3.96M +$2.01M +887,218 +103%
Acadian Asset Management
24
Acadian Asset Management
Massachusetts
$3.53M -$3.81M -1,676,999 -52%
SCM
25
Soleus Capital Management
Connecticut
$2.96M +$2.96M +1,304,300 New
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