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CytomX Therapeutics

66 hedge funds and large institutions have $28.8M invested in CytomX Therapeutics in 2025 Q1 according to their latest regulatory filings, with 7 funds opening new positions, 20 increasing their positions, 26 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

3.17% less ownership

Funds ownership: 59.69%56.52% (-3.2%)

6% less funds holding

Funds holding: 7066 (-4)

23% less repeat investments, than reductions

Existing positions increased: 20 | Existing positions reduced: 26

36% less first-time investments, than exits

New positions opened: 7 | Existing positions closed: 11

40% less capital invested

Capital invested by funds: $48.1M → $28.8M (-$19.3M)

70% less call options, than puts

Call options by funds: $9K | Put options by funds: $30K

Holders
66
Holders Change
-4
Holders Change %
-5.71%
% of All Funds
0.89%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
7
Increased
20
Reduced
26
Closed
11
Calls
$9K
Puts
$30K
Net Calls
-$21K
Net Calls Change
-$52K
Name Holding Trade Value Shares
Change
Change in
Stake
TCM
1
Tang Capital Management
California
$4.27M -$461K -593,935 -8%
BI
2
BVF Inc
California
$3.32M
Vanguard Group
3
Vanguard Group
Pennsylvania
$3.25M -$34.8K -44,926 -0.9%
PM
4
Prosight Management
Texas
$2.5M +$19.4K +25,008 +0.6%
Acadian Asset Management
5
Acadian Asset Management
Massachusetts
$2.05M +$75.2K +96,989 +3%
Millennium Management
6
Millennium Management
New York
$1.8M -$306K -394,736 -12%
Point72 Asset Management
7
Point72 Asset Management
Connecticut
$1.68M
WP
8
Woodline Partners
California
$1.05M +$1.29M +1,657,306 New
LCM
9
Laurion Capital Management
New York
$823K +$35.1K +45,322 +4%
BlackRock
10
BlackRock
New York
$742K -$56.9K -73,394 -6%
Renaissance Technologies
11
Renaissance Technologies
New York
$735K -$148K -190,800 -14%
RCM
12
RA Capital Management
Massachusetts
$636K +$775K +1,000,000 New
Geode Capital Management
13
Geode Capital Management
Massachusetts
$546K +$32.8K +42,315 +5%
GCP
14
GSA Capital Partners
United Kingdom
$485K +$561K +724,045 +1,862%
UBS Group
15
UBS Group
Switzerland
$475K +$185K +238,232 +47%
Assenagon Asset Management
16
Assenagon Asset Management
Luxembourg
$452K +$86.5K +111,604 +19%
Jacobs Levy Equity Management
17
Jacobs Levy Equity Management
New Jersey
$436K -$668K -861,007 -56%
CPC
18
Congress Park Capital
New York
$428K -$226K -290,904 -30%
SSA
19
Schonfeld Strategic Advisors
New York
$375K -$614K -791,468 -57%
SEI Investments
20
SEI Investments
Pennsylvania
$310K
Bank of America
21
Bank of America
North Carolina
$295K +$358K +461,833 +22,852%
FAM
22
Formidable Asset Management
Ohio
$225K -$22.2K -28,689 -7%
TI
23
Tidal Investments
Wisconsin
$225K -$22.2K -28,689 -7%
State Street
24
State Street
Massachusetts
$203K
BCM
25
Bridgeway Capital Management
Texas
$195K -$19.4K -25,000 -8%

CTMX Hedge Fund Activity: Q1 2025 in Review

66 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in CytomX Therapeutics (CTMX) for Q1 2025, worth a combined $28.8M — down 40% from $48.1M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of CTMX and 7 opened new positions — a net loss of 4 holders — while 26 trimmed existing stakes and 20 added.

The largest buyer was Woodline Partners, opening a new position worth an estimated $1.29M. The largest seller was Jacobs Levy Equity Management, cutting an estimated $668K.

  • 66 institutional investors held CytomX Therapeutics (CTMX) as of Q1 2025, down from 70 in Q4 2024.
  • Funds reported $28.8M of CytomX Therapeutics stock for Q1 2025, down 40% quarter-over-quarter.
  • 7 funds opened new CytomX Therapeutics positions in Q1 2025 and 11 closed out, a net change of -4 holders.
  • The largest CytomX Therapeutics buyer in Q1 2025 was Woodline Partners, an estimated $1.29M added.
  • The largest CytomX Therapeutics seller in Q1 2025 was Jacobs Levy Equity Management, an estimated $668K sold.

Based on aggregated 13F filings for Q1 2025.