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CytomX Therapeutics

66 hedge funds and large institutions have $28.8M invested in CytomX Therapeutics in 2025 Q1 according to their latest regulatory filings, with 7 funds opening new positions, 20 increasing their positions, 26 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

3.17% less ownership

Funds ownership: 59.69%56.52% (-3.2%)

6% less funds holding

Funds holding: 7066 (-4)

23% less repeat investments, than reductions

Existing positions increased: 20 | Existing positions reduced: 26

36% less first-time investments, than exits

New positions opened: 7 | Existing positions closed: 11

40% less capital invested

Capital invested by funds: $48.1M → $28.8M (-$19.3M)

70% less call options, than puts

Call options by funds: $9K | Put options by funds: $30K

Holders
66
Holders Change
-4
Holders Change %
-5.71%
% of All Funds
0.89%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
7
Increased
20
Reduced
26
Closed
11
Calls
$9K
Puts
$30K
Net Calls
-$21K
Net Calls Change
-$52K
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of New York Mellon
26
Bank of New York Mellon
New York
$154K
Northern Trust
27
Northern Trust
Illinois
$95.8K
AGP
28
Aspire Growth Partners
Florida
$88.6K +$39.9K +51,474 +126%
Two Sigma Investments
29
Two Sigma Investments
New York
$74.1K -$158K -204,292 -64%
Fidelity Investments
30
Fidelity Investments
Massachusetts
$68.9K -$154K -198,472 -65%
JP Morgan Chase
31
JP Morgan Chase
New York
$66.9K -$548K -706,336 -87%
FA
32
Forefront Analytics
Pennsylvania
$63.1K +$27.8K +35,811 +56%
Universal-Beteiligungs- und Servicegesellschaft
33
Universal-Beteiligungs- und Servicegesellschaft
Germany
$61.8K +$75.3K +97,123 New
Marshall Wace
34
Marshall Wace
United Kingdom
$54.7K +$66.3K +85,539 New
Prudential Financial
35
Prudential Financial
New Jersey
$51.8K +$13.3K +17,200 +27%
VCIM
36
Velan Capital Investment Management
Georgia
$47.7K +$31K +40,000 +114%
Goldman Sachs
37
Goldman Sachs
New York
$39.2K +$47.9K +61,719 New
Morgan Stanley
38
Morgan Stanley
New York
$38.5K +$36.7K +47,383 +359%
Qube Research & Technologies (QRT)
39
Qube Research & Technologies (QRT)
United Kingdom
$34.8K -$233 -300 -0.5%
Commonwealth Equity Services
40
Commonwealth Equity Services
Massachusetts
$34K +$775 +1,000 +2%
MFS
41
Miller Financial Services
Michigan
$32.4K +$20.2K +26,000 +104%
ACM
42
ADAR1 Capital Management
Texas
$29.9K -$76K -98,000 -68%
Russell Investments Group
43
Russell Investments Group
United Kingdom
$28.3K +$8.16K +10,522 +31%
PAG
44
Private Advisor Group
New Jersey
$28K
LPL Financial
45
LPL Financial
California
$26.9K
Simplex Trading
46
Simplex Trading
Illinois
$21K +$25.9K +33,346 +6,577%
TIA
47
Traphagen Investment Advisors
New Jersey
$19.4K
Susquehanna International Group
48
Susquehanna International Group
Pennsylvania
$18.3K -$24.1K -31,044 -52%
Charles Schwab
49
Charles Schwab
California
$15.8K +$47 +60 +0.2%
Jane Street
50
Jane Street
New York
$12.7K -$1.31K -1,691 -8%

CTMX Hedge Fund Activity: Q1 2025 in Review

66 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in CytomX Therapeutics (CTMX) for Q1 2025, worth a combined $28.8M — down 40% from $48.1M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of CTMX and 7 opened new positions — a net loss of 4 holders — while 26 trimmed existing stakes and 20 added.

The largest buyer was Woodline Partners, opening a new position worth an estimated $1.29M. The largest seller was Jacobs Levy Equity Management, cutting an estimated $668K.

  • 66 institutional investors held CytomX Therapeutics (CTMX) as of Q1 2025, down from 70 in Q4 2024.
  • Funds reported $28.8M of CytomX Therapeutics stock for Q1 2025, down 40% quarter-over-quarter.
  • 7 funds opened new CytomX Therapeutics positions in Q1 2025 and 11 closed out, a net change of -4 holders.
  • The largest CytomX Therapeutics buyer in Q1 2025 was Woodline Partners, an estimated $1.29M added.
  • The largest CytomX Therapeutics seller in Q1 2025 was Jacobs Levy Equity Management, an estimated $668K sold.

Based on aggregated 13F filings for Q1 2025.