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Crinetics Pharmaceuticals

222 hedge funds and large institutions have $3.01B invested in Crinetics Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 35 funds opening new positions, 95 increasing their positions, 65 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

634% more call options, than puts

Call options by funds: $3.14M | Put options by funds: $428K

46% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 65

2.16% more ownership

Funds ownership: 109.51%111.68% (+2.2%)

5% less first-time investments, than exits

New positions opened: 35 | Existing positions closed: 37

2% less funds holding

Funds holding: 227222 (-5)

12% less capital invested

Capital invested by funds: $3.42B → $3.01B (-$412M)

33% less funds holding in top 10

Funds holding in top 10: 96 (-3)

Holders
222
Holders Change
-5
Holders Change %
-2.2%
% of All Funds
2.92%
Holding in Top 10
6
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-33.33%
% of All Funds
0.08%
New
35
Increased
95
Reduced
65
Closed
37
Calls
$3.14M
Puts
$428K
Net Calls
+$2.71M
Net Calls Change
+$6.76M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$406M +$2.93M +94,730 +0.7%
Vanguard Group
2
Vanguard Group
Pennsylvania
$266M -$1.71M -55,468 -0.6%
BlackRock
3
BlackRock
New York
$213M -$7.35M -237,854 -3%
DCM
4
Driehaus Capital Management
Illinois
$184M +$4.94M +160,123 +3%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$167M -$33.5M -1,084,089 -16%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$161M +$14.8M +478,144 +9%
FCM
7
Farallon Capital Management
California
$134M +$1.27M +41,000 +0.9%
EC
8
EcoR1 Capital
California
$123M
Janus Henderson Group
9
Janus Henderson Group
United Kingdom
$98.1M -$436K -14,122 -0.4%
State Street
10
State Street
Massachusetts
$92.7M -$1.82M -58,969 -2%
PBA
11
Paradigm Biocapital Advisors
New York
$67.4M +$12.3M +397,385 +20%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$63.7M +$692K +22,393 +1%
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$57.5M +$37.7M +1,219,763 +157%
Jennison Associates
14
Jennison Associates
New York
$57.1M -$4.1M -132,649 -6%
SL
15
Siren LLC
Connecticut
$48.6M
NHAS
16
Novo Holdings A/S
Denmark
$44.6M +$8.49M +275,000 +22%
VPC
17
Vestal Point Capital
New York
$43.1M
Pictet Asset Management
18
Pictet Asset Management
Switzerland
$34.5M +$4.74M +153,462 +15%
O
19
OrbiMed
New York
$33M +$4.63M +150,000 +15%
GKIM
20
GW&K Investment Management
Massachusetts
$27.9M +$1.57M +50,790 +6%
Goldman Sachs
21
Goldman Sachs
New York
$25.9M +$12.4M +401,293 +80%
HRCM
22
Hood River Capital Management
Florida
$25.6M +$489K +15,835 +2%
FLAM
23
First Light Asset Management
Minnesota
$24.9M +$269K +8,717 +1%
American Century Companies
24
American Century Companies
Missouri
$24.4M +$3.99M +129,060 +18%
Northern Trust
25
Northern Trust
Illinois
$22.6M -$2.25M -72,868 -9%

CRNX Hedge Fund Activity: Q2 2025 in Review

222 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Crinetics Pharmaceuticals (CRNX) for Q2 2025, worth a combined $3.01B — down 12% from $3.42B a quarter earlier.

Sellers outnumbered buyers: 37 funds closed out of CRNX and 35 opened new positions — a net loss of 2 holders — while 65 trimmed existing stakes and 95 added.

The largest buyer was Point72 Asset Management, adding an estimated $37.7M. The largest seller was Wellington Management Group, cutting an estimated $33.5M.

  • 222 institutional investors held Crinetics Pharmaceuticals (CRNX) as of Q2 2025, down from 227 in Q1 2025.
  • Funds reported $3.01B of Crinetics Pharmaceuticals stock for Q2 2025, down 12% quarter-over-quarter.
  • 35 funds opened new Crinetics Pharmaceuticals positions in Q2 2025 and 37 closed out, a net change of -2 holders.
  • The largest Crinetics Pharmaceuticals buyer in Q2 2025 was Point72 Asset Management, an estimated $37.7M added.
  • The largest Crinetics Pharmaceuticals seller in Q2 2025 was Wellington Management Group, an estimated $33.5M sold.

Based on aggregated 13F filings for Q2 2025.