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Crinetics Pharmaceuticals

227 hedge funds and large institutions have $3.42B invested in Crinetics Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 90 increasing their positions, 73 reducing their positions, and 55 closing their positions.

New
Increased
Maintained
Reduced
Closed

23% more repeat investments, than reductions

Existing positions increased: 90 | Existing positions reduced: 73

2.02% more ownership

Funds ownership: 107.49%109.51% (+2%)

8% less funds holding

Funds holding: 247227 (-20)

33% less capital invested

Capital invested by funds: $5.1B → $3.42B (-$1.68B)

35% less first-time investments, than exits

New positions opened: 36 | Existing positions closed: 55

36% less funds holding in top 10

Funds holding in top 10: 149 (-5)

74% less call options, than puts

Call options by funds: $1.4M | Put options by funds: $5.45M

Holders
227
Holders Change
-20
Holders Change %
-8.1%
% of All Funds
3.04%
Holding in Top 10
9
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-35.71%
% of All Funds
0.12%
New
36
Increased
90
Reduced
73
Closed
55
Calls
$1.4M
Puts
$5.45M
Net Calls
-$4.05M
Net Calls Change
-$5.09M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$471M +$191M +5,103,183 +57%
Vanguard Group
2
Vanguard Group
Pennsylvania
$312M +$8.3M +222,209 +2%
BlackRock
3
BlackRock
New York
$257M +$5.28M +141,376 +2%
Wellington Management Group
4
Wellington Management Group
Massachusetts
$231M -$2.21M -59,170 -0.9%
DCM
5
Driehaus Capital Management
Illinois
$209M +$3.69M +98,888 +2%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$171M -$11.3M -302,145 -6%
FCM
7
Farallon Capital Management
California
$154M +$19.8M +530,000 +13%
EC
8
EcoR1 Capital
California
$144M
Janus Henderson Group
9
Janus Henderson Group
United Kingdom
$119M +$23.5M +629,001 +23%
State Street
10
State Street
Massachusetts
$110M +$10.9M +292,437 +10%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$73.5M +$3.44M +92,091 +4%
Jennison Associates
12
Jennison Associates
New York
$71.1M -$22M -588,584 -22%
PBA
13
Paradigm Biocapital Advisors
New York
$65.3M +$1.32M +35,407 +2%
SL
14
Siren LLC
Connecticut
$56.6M +$2.95M +78,959 +5%
VPC
15
Vestal Point Capital
New York
$50.3M +$56M +1,500,000 New
NHAS
16
Novo Holdings A/S
Denmark
$42.8M +$11.8M +314,785 +33%
Pictet Asset Management
17
Pictet Asset Management
Switzerland
$35.1M +$7.43M +198,965 +23%
O
18
OrbiMed
New York
$33.5M
Franklin Resources
19
Franklin Resources
California
$32.3M -$23.5M -628,385 -39%
GKIM
20
GW&K Investment Management
Massachusetts
$30.9M +$9M +240,897 +35%
HRCM
21
Hood River Capital Management
Florida
$29.3M +$793K +21,235 +2%
Northern Trust
22
Northern Trust
Illinois
$28.7M -$849K -22,733 -3%
FLAM
23
First Light Asset Management
Minnesota
$28.7M -$1.12M -30,034 -3%
Point72 Asset Management
24
Point72 Asset Management
Connecticut
$26.1M -$75.1M -2,010,541 -72%
Fisher Asset Management
25
Fisher Asset Management
Washington
$25.9M +$7.99M +214,060 +38%

CRNX Hedge Fund Activity: Q1 2025 in Review

227 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Crinetics Pharmaceuticals (CRNX) for Q1 2025, worth a combined $3.42B — down 33% from $5.1B a quarter earlier.

Sellers outnumbered buyers: 55 funds closed out of CRNX and 36 opened new positions — a net loss of 19 holders — while 73 trimmed existing stakes and 90 added.

The largest buyer was Fidelity Investments, adding an estimated $191M. The largest seller was Point72 Asset Management, cutting an estimated $75.1M.

  • 227 institutional investors held Crinetics Pharmaceuticals (CRNX) as of Q1 2025, down from 247 in Q4 2024.
  • Funds reported $3.42B of Crinetics Pharmaceuticals stock for Q1 2025, down 33% quarter-over-quarter.
  • 36 funds opened new Crinetics Pharmaceuticals positions in Q1 2025 and 55 closed out, a net change of -19 holders.
  • The largest Crinetics Pharmaceuticals buyer in Q1 2025 was Fidelity Investments, an estimated $191M added.
  • The largest Crinetics Pharmaceuticals seller in Q1 2025 was Point72 Asset Management, an estimated $75.1M sold.

Based on aggregated 13F filings for Q1 2025.