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Crinetics Pharmaceuticals
CRNX

222 hedge funds and large institutions have $3.01B invested in Crinetics Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 35 funds opening new positions, 95 increasing their positions, 65 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

634% more call options, than puts

Call options by funds: $3.14M | Put options by funds: $428K

46% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 65

2.16% more ownership

Funds ownership: 109.51% → 111.68% (+2.2%)

5% less first-time investments, than exits

New positions opened: 35 | Existing positions closed: 37

2% less funds holding

Funds holding: 227 → 222 (-5)

12% less capital invested

Capital invested by funds: $3.42B → $3.01B (-$412M)

33% less funds holding in top 10

Funds holding in top 10: 9 → 6 (-3)

Holders
222
Holders Change
-5
Holders Change %
-2.2%
% of All Funds
2.92%
Holding in Top 10
6
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-33.33%
% of All Funds
0.08%
New
35
Increased
95
Reduced
65
Closed
37
Calls
$3.14M
Puts
$428K
Net Calls
+$2.71M
Net Calls Change
+$6.76M

Top Buyers

Rank Fund Capital Flow
1
Point72 Asset Management
Point72 Asset Management
Connecticut
+$37.7M
2
Citadel Advisors
Citadel Advisors
Florida
+$19M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$14.8M
4
RI
RTW Investments
New York
+$14.4M
5
Goldman Sachs
Goldman Sachs
New York
+$12.4M

Top Sellers

Rank Fund Capital Flow
1
Wellington Management Group
Wellington Management Group
Massachusetts
-$33.5M
2
SG Americas Securities
SG Americas Securities
New York
-$15.5M
3
LGM
Logos Global Management
California
-$11.7M
4
Franklin Resources
Franklin Resources
California
-$9.7M
5
VOYA Investment Management
VOYA Investment Management
Georgia
-$9.56M
Name Holding Trade Value Shares
Change 		Change in
Stake
BFM
76
Boothbay Fund Management
New York
$3.13M -$957K -31,004 -22%
Jane Street
77
Jane Street
New York
$2.97M +$3.19M +103,296 New
Legal & General Group
78
Legal & General Group
United Kingdom
$2.81M +$275K +8,905 +10%
Verition Fund Management
79
Verition Fund Management
Connecticut
$2.74M +$2.13M +68,875 +260%
AIC
80
AWM Investment Company
New York
$2.73M – – –
AllianceBernstein
81
AllianceBernstein
Tennessee
$2.68M -$545K -17,654 -16%
Rafferty Asset Management
82
Rafferty Asset Management
New York
$2.61M -$351K -11,375 -11%
Wells Fargo
83
Wells Fargo
California
$2.59M -$44.3K -1,434 -2%
Invesco
84
Invesco
Georgia
$2.25M +$253K +8,181 +12%
California State Teachers Retirement System (CalSTRS)
85
California State Teachers Retirement System (CalSTRS)
California
$2.17M +$15K +487 +0.6%
PHP
86
Parkman Healthcare Partners
Connecticut
$2.11M +$293K +9,472 +15%
Two Sigma Advisers
87
Two Sigma Advisers
New York
$1.94M +$1.88M +61,000 +968%
State of Wisconsin Investment Board
88
State of Wisconsin Investment Board
Wisconsin
$1.86M +$31.9K +1,032 +2%
EAM
89
Exome Asset Management
New York
$1.8M +$352K +11,405 +22%
State of New Jersey Common Pension Fund D
90
State of New Jersey Common Pension Fund D
New Jersey
$1.8M +$206K +6,674 +12%
SEI Investments
91
SEI Investments
Pennsylvania
$1.73M +$169K +5,466 +10%
NIM
92
NEOS Investment Management
Connecticut
$1.67M -$21.8K -706 -1%
TE
93
Tema ETFs
New York
$1.67M -$21.8K -706 -1%
Citigroup
94
Citigroup
New York
$1.63M -$2.88M -93,271 -62%
Envestnet Asset Management
95
Envestnet Asset Management
Illinois
$1.56M -$75.1K -2,433 -4%
Mirae Asset Global ETFs Holdings
96
Mirae Asset Global ETFs Holdings
Hong Kong
$1.56M -$164K -5,316 -9%
MIM
97
MetLife Investment Management
New Jersey
$1.54M – – –
ACM
98
ADAR1 Capital Management
Texas
$1.53M – – –
Two Sigma Investments
99
Two Sigma Investments
New York
$1.52M +$1.63M +52,779 New
AA
100
ALPS Advisors
Colorado
$1.45M -$518K -16,779 -25%
2 3
4
5 6

CRNX Hedge Fund Activity: Q2 2025 in Review

222 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Crinetics Pharmaceuticals (CRNX) for Q2 2025, worth a combined $3.01B — down 12% from $3.42B a quarter earlier.

Sellers outnumbered buyers: 37 funds closed out of CRNX and 35 opened new positions — a net loss of 2 holders — while 65 trimmed existing stakes and 95 added.

The largest buyer was Point72 Asset Management, adding an estimated $37.7M. The largest seller was Wellington Management Group, cutting an estimated $33.5M.

  • 222 institutional investors held Crinetics Pharmaceuticals (CRNX) as of Q2 2025, down from 227 in Q1 2025.
  • Funds reported $3.01B of Crinetics Pharmaceuticals stock for Q2 2025, down 12% quarter-over-quarter.
  • 35 funds opened new Crinetics Pharmaceuticals positions in Q2 2025 and 37 closed out, a net change of -2 holders.
  • The largest Crinetics Pharmaceuticals buyer in Q2 2025 was Point72 Asset Management, an estimated $37.7M added.
  • The largest Crinetics Pharmaceuticals seller in Q2 2025 was Wellington Management Group, an estimated $33.5M sold.

Based on aggregated 13F filings for Q2 2025.