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Crinetics Pharmaceuticals

225 hedge funds and large institutions have $4.49B invested in Crinetics Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 41 funds opening new positions, 86 increasing their positions, 73 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

416% more call options, than puts

Call options by funds: $45.9M | Put options by funds: $8.9M

49% more capital invested

Capital invested by funds: $3.01B → $4.49B (+$1.48B)

33% more funds holding in top 10

Funds holding in top 10: 68 (+2)

18% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 73

17% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 35

2.69% more ownership

Funds ownership: 111.68%114.37% (+2.7%)

1% more funds holding

Funds holding: 222225 (+3)

Holders
225
Holders Change
+3
Holders Change %
+1.35%
% of All Funds
2.95%
Holding in Top 10
8
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+33.33%
% of All Funds
0.1%
New
41
Increased
86
Reduced
73
Closed
35
Calls
$45.9M
Puts
$8.9M
Net Calls
+$37M
Net Calls Change
+$34.3M
Name Holding Trade Value Shares
Change
Change in
Stake
Deutsche Bank
51
Deutsche Bank
Germany
$9.68M +$1.19M +37,169 +19%
UBS AM
52
UBS AM
Illinois
$9.07M -$3.74M -117,106 -35%
Millennium Management
53
Millennium Management
New York
$9.01M -$4.52M -141,433 -40%
HSBC Holdings
54
HSBC Holdings
United Kingdom
$8.78M +$6.51M +203,624 +2,829%
TD Asset Management
55
TD Asset Management
Ontario, Canada
$8.48M +$34.1K +1,066 +0.5%
Barclays
56
Barclays
United Kingdom
$7.63M -$3.48M -108,811 -37%
SBH
57
Segall Bryant & Hamill
Illinois
$7.53M +$139K +4,332 +2%
Skandinaviska Enskilda Banken (SEB)
58
Skandinaviska Enskilda Banken (SEB)
Sweden
$7.44M +$5.13M +160,467 +886%
SCM
59
Sio Capital Management
New York
$7.28M +$5.59M +174,841 New
RHJA
60
Rice Hall James & Associates
California
$7.25M +$5.57M +174,077 New
Swiss National Bank
61
Swiss National Bank
Switzerland
$7.18M +$118K +3,700 +2%
Royal Bank of Canada
62
Royal Bank of Canada
Ontario, Canada
$7.1M -$63.4K -1,984 -1%
Russell Investments Group
63
Russell Investments Group
United Kingdom
$6.21M -$237K -7,401 -5%
New York State Common Retirement Fund
64
New York State Common Retirement Fund
New York
$6.18M +$235K +7,359 +5%
Manulife (Manufacturers Life Insurance)
65
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$6.16M -$229K -7,167 -5%
DC
66
Decheng Capital
California
$5.96M
NLVP
67
New Leaf Venture Partners
New York
$5.87M
RhumbLine Advisers
68
RhumbLine Advisers
Massachusetts
$5.48M -$121K -3,785 -3%
IC
69
Ikarian Capital
Texas
$5.45M -$9.67M -302,529 -70%
MAP
70
Moody Aldrich Partners
Massachusetts
$4.81M -$712K -22,253 -16%
AIC
71
AWM Investment Company
New York
$4.17M +$160K +5,000 +5%
Wells Fargo
72
Wells Fargo
California
$4.11M +$276K +8,642 +10%
Legal & General Group
73
Legal & General Group
United Kingdom
$3.91M -$119K -3,723 -4%
AllianceBernstein
74
AllianceBernstein
Tennessee
$3.87M
Schroder Investment Management Group
75
Schroder Investment Management Group
United Kingdom
$3.8M -$1.72M -53,660 -38%

CRNX Hedge Fund Activity: Q3 2025 in Review

225 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Crinetics Pharmaceuticals (CRNX) for Q3 2025, worth a combined $4.49B — up 49% from $3.01B a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new CRNX positions and 35 closed out — a net gain of 6 holders — while 86 added to existing stakes and 73 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $82.3M. The largest seller was State Street, cutting an estimated $32.5M.

  • 225 institutional investors held Crinetics Pharmaceuticals (CRNX) as of Q3 2025, up from 222 in Q2 2025.
  • Funds reported $4.49B of Crinetics Pharmaceuticals stock for Q3 2025, up 49% quarter-over-quarter.
  • 41 funds opened new Crinetics Pharmaceuticals positions in Q3 2025 and 35 closed out, a net change of +6 holders.
  • The largest Crinetics Pharmaceuticals buyer in Q3 2025 was Wellington Management Group, an estimated $82.3M added.
  • The largest Crinetics Pharmaceuticals seller in Q3 2025 was State Street, an estimated $32.5M sold.

Based on aggregated 13F filings for Q3 2025.